The Sheridan Libraries and the Welch Medical Library of Johns Hopkins University are pleased to announce the availability of the Johns Hopkins Libraries Open Access Promotion Fund. The intent of the fund is to promote open access publishing by Hopkins researchers by reimbursing the author fees often required by open access publishers.
The fund consists of a set amount of monies that will, on a yearly basis, be disbursed until depleted.
Browsing JHU Libraries Open Access Fund by Author "Armand, Mehran"
(PLoS Organization, 2013-06-26) Basafa, Ehsan; Murphy, Ryan J.; Kutzer, Michael D.; Otake, Yoshito; Armand, Mehran
Femoroplasty is a potential preventive treatment for osteoporotic hip fractures. It involves augmenting mechanical properties of the femur by injecting Polymethylmethacrylate (PMMA) bone cement. To reduce the risks involved and maximize the outcome, however, the procedure needs to be carefully planned and executed. An important part of the planning system is predicting infiltration of cement into the porous medium of cancellous bone. We used the method of Smoothed Particle Hydrodynamics (SPH) to model the flow of PMMA inside porous media. We modified the standard formulation of SPH to incorporate the extreme viscosities associated with bone cement. Darcy creeping flow of fluids through isotropic porous media was simulated and the results were compared with those reported in the literature. Further validation involved injecting PMMA cement inside porous foam blocks - osteoporotic cancellous bone surrogates - and simulating the injections using our proposed SPH model. Millimeter accuracy was obtained in comparing the simulated and actual cement shapes. Also, strong correlations were found between the simulated and the experimental data of spreading distance (R2 = 0.86) and normalized pressure (R2 = 0.90). Results suggest that the proposed model is suitable for use in an osteoporotic femoral augmentation planning framework.