Now showing items 1-4 of 4

    • Identification of Novel F-Box Proteins that Regulate Caenorhabditis elegans Synapsis 

      Bae, Jung Woo; 0000-0001-5745-4896 (Johns Hopkins UniversityUSA, 2022-04-15)
      Meiosis is a specialized type of cell division that lays the foundation of propagation for all sexually reproducing lifeforms. During meiotic prophase, a proteinaceous structure called the synaptonemal complex (SC) assembles ...
    • INTERROGATING THE REGULATION OF THE MIR-35 FAMILY OF MICRORNAS IN C. ELEGANS 

      Donnelly, Bridget Fleming (Johns Hopkins UniversityUSA, 2022-03-31)
      MicroRNA (miRNA) abundance is tightly controlled by regulation of biogenesis and decay. While there is much known about the biogenesis and functions of miRNAs, very little is known about the decay mechanisms of miRNAs. The ...
    • Regulation and Function of P granule dynamics during germline development in C. elegans 

      Wang, Jennifer T. (Johns Hopkins UniversityUSA, 2014-03-26)
      Germ granules are conserved cytoplasmic RNA-protein particles unique to the germline. We have used C. elegans germ granules, known as P granules, as a model system to understand the function and regulation of germ granules ...
    • REGULATION OF P GRANULES BY THE DISORDERED PROTEIN MEG-3 

      Schmidt, Helen Frances; 0000-0002-3449-2790 (Johns Hopkins UniversityUSA, 2020-12-10)
      C. elegans P granules are RNA granules which form in the zygote and are preferentially segregated to the germ cell lineage as the embryo develops. Formation of P granules in the embryo requires the intrinsically disordered ...