Now showing items 1-4 of 4

    • Direction Sensing During Collective Cell Migration 

      Cai, Danfeng (Johns Hopkins UniversityUSA, 2014-10-06)
      Collective cell migration is an important process not only in development but also in diseases. The Drosophila ovary, with its relatively simply structure, genetic tractability, and the compatibility with live imaging, is ...
    • E-cadherin promotes hyper-proliferation in multiple models of breast cancer 

      Russo, Gabriella C (Johns Hopkins UniversityUSA, 2022-02-16)
      Despite decades of advancements in anti-cancer therapies, there are still many cancer subtypes that elude modern treatments. The lack of accurate in vitro models, which are necessary to better study cancer progression and ...
    • Molecular and cellular regulation of mammary epithelial dissemination 

      Shamir, Eliah Ruth (Johns Hopkins UniversityUSA, 2014-08-14)
      Dissemination of epithelial cancer cells represents the first step in metastatic spread. One postulated mechanism for dissemination is activation of an epithelial to mesenchymal transition (EMT), in which repression of the ...
    • The Role of the Secretory Pathway Ca2+-ATPase, SPCA2 in Breast Cancer Evolution 

      Dang, Donna K; 0000-0002-3001-8151 (Johns Hopkins UniversityUSA, 2018-03-27)
      Calcium dysregulation in breast cancer can occur early during dysplasia in mammary tissue, and persist throughout the progression of cancer. This perturbation to the homeostasis of calcium can be detrimental to the normal ...