Browsing by Subject "Vaccine"
Now showing items 1-4 of 4
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Development of prophylactic human papillomavirus vaccines
(Johns Hopkins University, 2014-05-28)The demonstration of the etiologic role of oncogenic type HPV infection in cervical cancer has led to the development of the prophylactic vaccines Cervarix and Gardasil. Despite their licensure, current vaccines do not ... -
How Pregnant Women in the United States Perceive Vaccines for Themselves, their Close Contacts and their Children
(Johns Hopkins UniversityUSA, 2019-01-04)Vaccine hesitancy has grown in recent decades [1-4], leading to the clustering of vaccine refusal and associated outbreaks of vaccine preventable diseases (VPDs) [5-11]. Vaccination rates of pregnant women in particular ... -
POINT MUTATIONS ON THE HEMAGGLUTININ OF THE 2015-2016 H1N1 LIVE ATTENUATED INFLUENZA VACCINE STRAIN AND THEIR EFFECT ON VIRAL REPLICATION
(Johns Hopkins UniversityUSA, 2022-05-04)The H1N1 component of the FluMist quadrivalent live attenuated influenza vaccine (QLAIV) for the 2015-2016 flu season had a lower replicative fitness in comparison to the other components in the formulation. This contributed ... -
The Role of TLR7 in Mediating Sex Differences in Response to Influenza Infection and Vaccination
(Johns Hopkins UniversityUSA, 2018-04-26)Among adult humans, females reportedly have more severe morbidity than males following exposure to novel strains of influenza A viruses (e.g., pandemic or avian influenza viruses). Females also have higher antibody titers ...