Now showing items 1-10 of 14
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia
(National Academy of Sciences, 1993-08-01)
The existence of water-selective channels has been postulated to explain the high water permeability of erythrocytes and certain epithelial cells. The aquaporin CHIP (channel-forming integral membrane protein of 28 kDa), ...
Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
(National Academy of Sciences, 1999-05-01)
All characterized mammalian aquaporins (AQPs) are localized to plasma membranes where they function chiefly to mediate water transport across cells. Here we show that AQP6 is localized exclusively in intracellular membranes ...
Aquaporins and the respiratory system: advice for a lung investigator
(American Society for Clinical Investigation, 2000-01-01)
Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: Mechanisms for aquaporin 2 down-regulation and cellular proliferation
(National Academy of Sciences, 2008-03-04)
Lithium is a commonly prescribed mood-stabilizing drug. However, chronic treatment with lithium induces numerous kidney-related side effects, such as dramatically reduced aquaporin 2 (AQP2) abundance, altered renal function, ...
Concurrent expression of erythroid and renal aquaporin CHIP and appearance of water channel activity in perinatal rats
(American Society for Clinical Investigation, 1993-10)
Major phenotypic changes occur in red cell membranes during the perinatal period, but the underlying molecular explanations remain poorly defined. Aquaporin CHIP, the major erythroid and renal water channel, was studied ...
Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence
(National Academy of Sciences, 2007-07-24)
Human and rodent erythrocytes are known to be highly permeable to glycerol. Aquaglyceroporin aquaporin (AQP)3 is the major glycerol channel in human and rat erythrocytes. However, AQP3 expression has not been observed in ...
Targeted disruption of the Cl−/HCO3− exchanger Ae2 results in osteopetrosis in mice
(National Academy of Sciences, 2009-02-03)
Osteoclasts are multinucleated bone-resorbing cells responsible for constant remodeling of bone tissue and for maintaining calcium homeostasis. The osteoclast creates an enclosed space, a lacuna, between their ruffled ...
Aquaporin-1 Water Channel Expression in Human Kidney
(American Society for Nephrology, 1997-01)
The pattern of aquaporin-1 water channel protein (AQP1) expression in the human kidney was analyzed by immunocytochemistry using semi-thin and optimized high-resolution immunoelectron microscopy based on freeze-substituted ...
Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat
(American Society for Clinical Investigation, 1996-05-15)
At birth water is rapidly reabsorbed from the distal lung in preparation for alveolar gas exchange. To investigate a potential role for the AQP1 water channel in development, lung membranes from fetal and perinatal rats ...
Genomic organization and developmental expression of aquaporin-5 in lung
(American College of Chest Physicians, 1997-06)