Now showing items 1-10 of 19
Quantification of Aquaporin-CHIP water channel protein in microdissected renal tubules by fluorescence-based ELISA
(American Society for Clinical Investigation, 1995-01)
Several transporters have been localized along the nephron by physiological methods or immunocytochemistry. However, the actual abundance of these molecules has not been established. To accomplish this goal, we have developed ...
Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer silimar to channel proteins
(American Society for Biochemistry and Molecular Biology, 1991-04-05)
A novel Mr 28,000 erythrocyte transmembrane protein was recently purified and found to exist in two forms, "28kDa" and "gly28kDa," the latter containing N-linked carbohydrate (Denker, B. M., Smith, B. L., Kuhajda, F. P., ...
Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein
(American Chemical Society, 1992)
The three-dimensional structure of aquaporin-1
(Nature Publishing Group, 1997-06-05)
The entry and exit of water from cells is a fundamental process of life. Recognition of the high water permeability of red blood cells led to the proposal that specialized water pores exist in the plasma membrane. Expression ...
Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens
(American Society for Clinical Investigation, 1994-09)
Blood group antigens are structural variants in surface carbohydrate or amino acid polymorphisms on extracellular domains of membrane proteins. The red cell water channel-forming integral protein (Aquaporin CHIP) is a ...
Developmental gene expression and tissue distribution of the CHIP28 water-channel protein
(National Academy of Sciences, 1993-05-15)
The CHIP28 water channel is a major component of red cell and renal tubule membranes; however, its ontogeny and tissue distribution remain undefined. Three patterns of expression were identified when CHIP28 mRNA was surveyed ...
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia
(National Academy of Sciences, 1993-08-01)
The existence of water-selective channels has been postulated to explain the high water permeability of erythrocytes and certain epithelial cells. The aquaporin CHIP (channel-forming integral membrane protein of 28 kDa), ...
Localization of aquaporin CHIP in the human eye: implications in the pathogenesis of glaucoma and other disorders of ocular fluid balance
(Association for Research in Vision and Opthalmology, 1994-10)
PURPOSE. The existence of integral membrane proteins that serve as selective water channels has been postulated to explain the movement of water across plasma membranes. Aquaporin CHIP (channel-forming integral membrane ...
Biochemistry of the erythrocyte Rh polypeptides: a review
(Yale School of Medicine, 1990-09)
The clinically important Rh blood group system is complex, consisting of multiple distinct antigens. Despite clinical recognition for over 50 years, the Rh blood group antigens have remained poorly understood on a molecular ...
Concurrent expression of erythroid and renal aquaporin CHIP and appearance of water channel activity in perinatal rats
(American Society for Clinical Investigation, 1993-10)
Major phenotypic changes occur in red cell membranes during the perinatal period, but the underlying molecular explanations remain poorly defined. Aquaporin CHIP, the major erythroid and renal water channel, was studied ...