Now showing items 1-10 of 69
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain
(National Academy of Sciences, 1996-10-01)
The aquaporin family of membrane water transport proteins are expressed in diverse tissues, and in brain the predominant water channel protein is AQP4. Here we report the isolation and characterization of the human AQP4 ...
The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel
(American Society for Biochemistry and Molecular Biology, 1993-01-05)
Water channels provide the plasma membranes of red cells and renal proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Molecular identification of ...
Aquaporin-1 Water Channel Expression in Human Kidney
(American Society for Nephrology, 1997-01)
The pattern of aquaporin-1 water channel protein (AQP1) expression in the human kidney was analyzed by immunocytochemistry using semi-thin and optimized high-resolution immunoelectron microscopy based on freeze-substituted ...
Regulation of the Escherichia coli water channel gene aqpZ
(National Academy of Sciences, 1998-03-31)
Osmotic movement of water across bacterial cell membranes is postulated to be a homeostatic mechanism for maintaining cell turgor. The molecular water transporter remained elusive until discovery of the Escherichia coli ...
Water channel properties of major intrinsic protein of lens
(American Society for Biochemistry and Molecular Biology, 1995-04-14)
The functions of major intrinsic protein (MIP) of lens are still unresolved; however the sequence homology with channel-forming integral membrane protein (CHIP) and other Aquaporins suggests that MIP is a water channel. ...
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
(National Academy of Sciences, 1998-09-29)
Aquaporin (AQP) water channels are abundant in the brain and spinal cord, where AQP1 and AQP4 are believed to play major roles in water metabolism and osmoregulation. Immunocytochemical analysis of the brain recently ...
Specialized membrane domains for water transport in glial cells: high resolution immunogold cytochemistry of aquaporin-4 in rat brain
(Copyright held by the original publisher: Journal of Neuroscience, 1997-01-01)
Membrane water transport is critically involved in brain volume homeostasis and in the pathogenesis of brain edema. The cDNA encoding aquaporin-4 (AQP4) water channel protein was recently isolated from rat brain. We used ...
The Aquaporins, Blueprints for Cellular Plumbing Systems
(American Society for Biochemistry and Molecular Biology, 1998-06-12)
Linkage of dominant hereditary spherocytosis to the gene for the erythrocyte membrane-skeleton protein ankyrin
(Massachusetts Medical Society, 1990-10-11)
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family
(National Academy of Sciences, 1991-12-15)
CHIP28 is a 28-kDa integral membrane protein with similarities to membrane channels and is found in erythrocytes and renal tubules. A cDNA for CHIP28 was isolated from human fetal liver cDNA template by a three-step ...