Now showing items 1-10 of 12
The human Aquaporin-5 gene. Molecular characterization and chromosomal localization.
(American Society for Biochemistry and Molecular Biology, 1996-04-12)
The cDNA for the fifth mammalian aquaporin (AQP5) was isolated from rat, and expression was demonstrated in rat salivary and lacrimal glands, cornea, and lung (Raina, S., Preston, G. M., Guggino, W. B., and Agre, P. (1995) ...
Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution
(National Academy of Sciences, 2005-02-08)
Aquaporin (AQP) 6 belongs to the aquaporin water channel family. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly ...
Functional impairment of lens aquaporin in two families with dominantly inherited cataracts
(Oxford University Press, 2000-09-22)
Opacities in the crystalline lens of eye appear with high frequency in the general population. Dominantly inherited cataracts with differing clinical features were found in two families carrying different point mutations ...
Molecular cloning and characterization of AqpZ, a water channel from Escherichia coli
(American Society for Biochemistry and Molecular Biology, 1995-12-08)
The aquaporin family of molecular water channels is widely expressed throughout the plant and animal kingdoms. No bacterial aquaporins are known; however, sequence-related bacterial genes have been identified that encode ...
Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
(National Academy of Sciences, 1997-04-01)
A replication-deficient, recombinant adenovirus encoding human aquaporin-1 (hAQP1), the archetypal water channel, was constructed. This virus, AdhAQP1, directed hAQP1 expression in several epithelial cell lines in vitro. ...
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family
(National Academy of Sciences, 1991-12-15)
CHIP28 is a 28-kDa integral membrane protein with similarities to membrane channels and is found in erythrocytes and renal tubules. A cDNA for CHIP28 was isolated from human fetal liver cDNA template by a three-step ...
Regulation of the Escherichia coli water channel gene aqpZ
(National Academy of Sciences, 1998-03-31)
Osmotic movement of water across bacterial cell membranes is postulated to be a homeostatic mechanism for maintaining cell turgor. The molecular water transporter remained elusive until discovery of the Escherichia coli ...
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain
(National Academy of Sciences, 1996-10-01)
The aquaporin family of membrane water transport proteins are expressed in diverse tissues, and in brain the predominant water channel protein is AQP4. Here we report the isolation and characterization of the human AQP4 ...
Genomic organization and developmental expression of aquaporin-5 in lung
(American College of Chest Physicians, 1997-06)
Aquaporin null phenotypes: The importance of classical physiology
(National Academy of Sciences, 1998-08-04)