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    Telomere dysfunction triggers developmentally regulated germ cell apoptosis 

    Greider, Carol W.; Chin, Lynda; DePinho, Ronald A.; Strong, Margaret A.; Rudolph, Karl Lenhard; Hemann, Michael T. (American Society for Cell Biology, 2001-07)
    Telomere dysfunction results in fertility defects in a number of organisms. Although data from fission yeast and Caenorhabditis elegans suggests that telomere dysfunction manifests itself primarily as defects in proper ...
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    The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability 

    Greider, Carol W.; Hao, Ling-Yang; Strong, Margaret A.; Hemann, Michael T. (Cell Press, 2001-10-05)
    Loss of telomere function can induce cell cycle arrest and apoptosis. To investigate the processes that trig- ger cellular responses to telomere dysfunction, we crossed mTR􏰀/􏰀 G6 mice that have short telomeres with mice ...
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    Wild-derived inbred mouse strains have short telomeres 

    Greider, Carol W.; Hemann, Michael T. (Oxford University Press, 2000-11-15)
    Telomere length and telomerase activity directly affect the replicative capacity of primary human cells. Some have suggested that telomere length influences organismal lifespan. We compared telomere length distributions ...
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    G-strand overhangs on telomeres in telomerase-deficient mouse cells 

    Greider, Carol W.; Hemann, Michael T. (Oxford University Press, 1999-10-15)
    Telomeres of eukaryotic chromosomes contain 3' overhangs which are thought to be essential for the maintenance of proper chromosome end structure and function. We examined the requirement for telomerase activity for the ...

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    Author
    Greider, Carol W. (4)
    Hemann, Michael T. (4)
    Strong, Margaret A. (2)Chin, Lynda (1)DePinho, Ronald A. (1)Hao, Ling-Yang (1)Rudolph, Karl Lenhard (1)SubjectElectrophoresis (2)Gel (2)Pulse-Field (2)Telomere/physiology (2)Apoptosis (1)Cell Survival (1)Chromosomes/physiology (1)DNA/genetics (1)In Situ Hybridization (1)In Situ Hybridization, Fluorescence (1)... View MoreDate Issued2001 (2)1999 (1)2000 (1)Has File(s)Yes (4)

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