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Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice

Nielsen, Søren; Frøkiær, Jørgen; Agre, Peter; Neely, ohn D; Dóczi, Tamas; Sulyok, Endre; Stødkilde-Jørgensen, Hans; Wertz, Karin; Füchtbauer, Ernst-Martin; Pedersen, Michael; Vajda, Zsolt (National Academy of Sciences, 2002-10-01)

Cerebral water accumulation was studied during induction of brain edema in dystrophin-null transgenic mice (mdx-betageo) and control mice. Immunofluorescence and immunoelectron microscopic analyses of dystrophin-null brains ...

Functional requirement of aquaporin-5 in plasma membranes of sweat glands

Nielsen, Søren; Agre, Peter C.; King, Landon S.; Menon, Anil G.; Krane, Carissa M.; Frøkiær, Jørgen; Fumagalli, Ornella; Jensen, Uffe B.; Kwon, Tae-Hwan; Nejsum, Lene N. (National Academy of Sciences, 2002-01-08)

The distribution and function of aquaporins (AQPs) have not previously been defined in sweat glands. In this study, AQP1, AQP3, and AQP5 mRNA were demonstrated in rat paw by reverse transcription (RT)-PCR, but AQP2 and ...