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Targeted disruption of the Cl−/HCO3− exchanger Ae2 results in osteopetrosis in mice
(National Academy of Sciences, 2009-02-03)
Osteoclasts are multinucleated bone-resorbing cells responsible for constant remodeling of bone tissue and for maintaining calcium homeostasis. The osteoclast creates an enclosed space, a lacuna, between their ruffled ...