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    Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. 

    DePinho, Ronald A.; Greider, Carol W.; Singer, Robert H.; Gottlieb, Geoffrey J.; Lee, Kee-Ho; Femino, Andrea; Chin, Lynda; Greenberg, Roger A. (Cell Press, 1999-05-14)
    Maintenance of telomere length is predicted to be essential for bypass of senescence and crisis checkpoints in cancer cells. The impact of telomere dysfunction on tumorigenesis was assessed in successive generations of ...

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    Author
    Chin, Lynda (1)
    DePinho, Ronald A. (1)Femino, Andrea (1)Gottlieb, Geoffrey J. (1)Greenberg, Roger A. (1)Greider, Carol W. (1)Lee, Kee-Ho (1)Singer, Robert H. (1)SubjectCyclin-Dependent Kinase Inhibitor p16/genetics (1)Neoplasms/etiology (1)
    Telomerase/metabolism (1)
    Telomere/physiology (1)... View MoreDate Issued1999 (1)Has File(s)
    Yes (1)

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