Now showing items 1-2 of 2

    • G-strand overhangs on telomeres in telomerase-deficient mouse cells 

      Greider, Carol W.; Hemann, Michael T. (Oxford University Press, 1999-10-15)
      Telomeres of eukaryotic chromosomes contain 3' overhangs which are thought to be essential for the maintenance of proper chromosome end structure and function. We examined the requirement for telomerase activity for the ...
    • Wild-derived inbred mouse strains have short telomeres 

      Greider, Carol W.; Hemann, Michael T. (Oxford University Press, 2000-11-15)
      Telomere length and telomerase activity directly affect the replicative capacity of primary human cells. Some have suggested that telomere length influences organismal lifespan. We compared telomere length distributions ...