Now showing items 1-3 of 3

    • A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA 

      Greider, Carol W.; Opperman, Kay Keyer; Chen, Jiunn-Liang (Oxford University Press, 2002-01-15)
      Telomerase is an enzyme that maintains telomere length by adding telomeric sequence repeats onto chromosome ends. The telomerase ribonucleoprotein complex consists of two essential components, a reverse transcriptase and ...
    • Gel shift and UV cross-linking analysis of Tetrahymena telomerase. 

      Greider, Carol; Crittenden, Jill; Hull, Christina; Harrington, Lea (American Society for Biochemistry and Molecular Biology, 1995-04-14)
      Telomerase is an unusual ribonucleoprotein that synthesizes new telomeres onto chromosome ends. The enzyme has been most extensively characterized in ciliates, where the RNA component has been cloned from several species, ...
    • Identification of two RNA-binding proteins associated with human telomerase RNA 

      Greider, Carol W.; Sternglanz, Rolf; Le, Siyuan (American Society for Cell Biology, 2000-03)
      Telomerase plays a crucial role in telomere maintenance in vivo. To understand telomerase regulation, we have been characterizing components of the enzyme. To date several components of the mammalian telomerase holoenzyme ...