Now showing items 1-2 of 2

    • Phosphorylation of H2AX at short telomeres in T cells and fibroblasts 

      Greider, Carol W.; Strong, Margaret A.; Hao, Ling-Yang (American Society for Biochemistry and Molecular Biology, 2004-10-22)
      Eukaryotic cells undergo arrest and enter apoptosis in response to short telomeres. T cells from late generation mTR(-/-) mice that lack telomerase show increased apoptosis when stimulated to enter the cell cycle. The ...
    • Short telomeres induce a DNA damage response in Saccharomyces cerevisiae 

      Greider, Carol W.; IJipma, Arne S. (American Society for Cell Biology, 2003-03)
      Telomerase-deficient Saccharomyces cerevisiae cells show a progressive decrease in telomere length. When grown for several days in log phase, the tlc1Delta cells initially display wild-type growth kinetics with subsequent ...