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    • Targeted disruption of the Cl−/HCO3− exchanger Ae2 results in osteopetrosis in mice 

      Praetorius, Jeppe; Nielsen, Søren; Agre, Peter; Frische, Sebastian; Gawenis, Lara R.; Kwon, Tae-Hwan; Fejerskov, Ole; Josephsen, Kaj (National Academy of Sciences, 2009-02-03)
      Osteoclasts are multinucleated bone-resorbing cells responsible for constant remodeling of bone tissue and for maintaining calcium homeostasis. The osteoclast creates an enclosed space, a lacuna, between their ruffled ...