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    • Targeted disruption of the Cl−/HCO3− exchanger Ae2 results in osteopetrosis in mice 

      Praetorius, J; Nielsen, S; Agre, P; Frische, S; Gawenis, L R; Kwon, T H; Fejerskov, O; Josephsen, K (National Academy of Sciences, 2009-02-03)
      Osteoclasts are multinucleated bone-resorbing cells responsible for constant remodeling of bone tissue and for maintaining calcium homeostasis. The osteoclast creates an enclosed space, a lacuna, between their ruffled ...