Now showing items 1-4 of 4

    • Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution 

      Yasui, M; Hazama, A; Agre, P; Kato, Y; Kozono, D; Liu, K (National Academy of Sciences, 2005-02-08)
      Aquaporin (AQP) 6 belongs to the aquaporin water channel family. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly ...
    • Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens 

      Agre, P; Anstee, D J; Spring, F A; Preston, G M; Smith, B L (American Society for Clinical Investigation, 1994-09)
      Blood group antigens are structural variants in surface carbohydrate or amino acid polymorphisms on extracellular domains of membrane proteins. The red cell water channel-forming integral protein (Aquaporin CHIP) is a ...
    • Molecular struture of the water channel through aquaporin CHIP. The hourglass model. 

      Smith, B L; Jung, J S; Preston, G M; Agre, P; Guggino, W B (American Society for Biochemistry and Molecular Biology, 1994-05-20)
      Aquaporin channel-forming integral protein (CHIP) is the first characterized water channel protein (genome symbol AQP1), but the molecular structure of the aqueous pathway through CHIP remains undefined. The two halves of ...
    • The three-dimensional structure of aquaporin-1 

      Engel, Andreas; Agre, Peter; Smith, Barbara L.; Fujiyoshi, Yoshinori; Mitsuoka, Kaoru; Heymann, J. Bernard; Murata, Kazuyoshi; Hirai, Teruhisa; Walz, Thomas (Nature Publishing Group, 1997-06-05)
      The entry and exit of water from cells is a fundamental process of life. Recognition of the high water permeability of red blood cells led to the proposal that specialized water pores exist in the plasma membrane. Expression ...