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Amyotrophic lateral sclerosis (ALS) induced changes in basigin expression patterns
(Office of the Provost, Johns Hopkins University, 2011)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive loss of motor function due to premature spinal and cortical motor neuron degeneration and death. Mutations in the ...
The Identification of Epigenetic Biomarkers for Myeloid Malignancies
(Office of the Provost, Johns Hopkins University, 2011)
Myeloid malignancies comprise a heterogeneous group of blood cancers that arise from abnormal stem or progenitor cells of the bone marrow and often portend a poor prognosis. The major disorders can be divided into four ...
Measles Virus Infection of Primary Respiratory Epithelial Cells Derived from Rhesus Macaques
(Office of the Provost, Johns Hopkins University, 2011)
Measles remains a leading vaccine-preventable cause of child mortality globally. Although a live-attenuated vaccine against measles virus (MV) is available, measles has been difficult to control. MV is a respiratory infection ...
Neuronal Differentiation of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells by Pulsed Electrical Field
(Office of the Provost, Johns Hopkins University, 2011)
This work surveyed the potential of using exogenous pulsed electrical field stimuli to guide the differentiation of human embryonic stem cell (hESC) derived-neural crest stem cells (NCSCs) towards their neuronal lineage. ...
Assessment of Pre-surgical Psychological Screening in Patients Undergoing Spine Surgery: Implementation and Clinical Impact
(Office of the Provost, Johns Hopkins University, 2010)
Technological Innovation and the Status of Modern Civil Legal Aid in the U.K.
(2010-04-20)
The status of technology used in the English legal aid system has previously been studied only in a limited manner. The Legal Services Research Centre (LSRC) has conducted civil justice surveys in 2001, 2004, 2006, and ...
Dynamics of magnetic monopoles in artificial spin ice
(Office of the Provost, Johns Hopkins University, 2011-05)
While finding the elementary magnetic monopole seems not an easy task, recently, scientists have come out an alternative approach by studying emergent particles in spin systems. Spin ice is a magnet with frustrated ...
Abuse during Pregnancy among African American & Afro-Caribbean Women
(The Johns Hopkins University, Office of the Provost, 2011)
Intimate Partner Violence (IPV) occurs in a relationship where one partner uses physical, emotional, or sexual abuse to control the other. IPV is “a serious criminal, social, and medical problem that has profound effects ...
Understanding Cancer Cell Motility and Interactions with the Extracellular Matrix
(2009-11)
The enzyme Transglutaminase is used as a novel method of increasing the stiffness of collagen gel without affecting other characteristics. This discovery has allowed for a more accurate analysis of cancer cell motility in ...
Exploring Transcriptional Silencing of Transposons in Zebrafish
(2010)
DNA methylation plays a critical role as an epigenetic
modifier in plants and mammals, however it is absent from many
invertebrate
genomes. Although DNA methylation is known to be present in zebrafish,
there is limited ...