Understanding Cancer Cell Motility and Interactions with the Extracellular Matrix

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Title: Understanding Cancer Cell Motility and Interactions with the Extracellular Matrix
Author: Wirtz, Denis; Fraley, Stephanie; Krishnamurthy, Ranjini
Abstract: The enzyme Transglutaminase is used as a novel method of increasing the stiffness of collagen gel without affecting other characteristics. This discovery has allowed for a more accurate analysis of cancer cell motility in a stiffer ECM leading to a potential understanding of the mechanism behind tumor metastasis.
URI: http://jhir.library.jhu.edu/handle/1774.2/34118
Date: 2009-11
Subject: 3D Collagen Gels
Transglutaminase
Extracellular Matrix

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