Understanding Cancer Cell Motility and Interactions with the Extracellular Matrix

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Date
2009-11
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Abstract
The enzyme Transglutaminase is used as a novel method of increasing the stiffness of collagen gel without affecting other characteristics. This discovery has allowed for a more accurate analysis of cancer cell motility in a stiffer ECM leading to a potential understanding of the mechanism behind tumor metastasis.
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Keywords
3D Collagen Gels, Transglutaminase, Extracellular Matrix
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