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Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer.
(PLoS Organizaton, 2013-05-08)
Triple negative breast cancers (TNBC) are difficult to treat due to a lack of targets and heterogeneity. Inhibition of angiogenesis is a promising therapeutic strategy, but has had limited effectiveness so far in breast ...
Characterizing optical properties of nano contrast agents by using cross-referencing OCT imaging.
(Optical Society of America, 2013-05-09)
We report a cross-referencing method to quickly and accurately characterize the optical properties of nanoparticles including the extinction, scattering, absorption and backscattering cross sections by using an OCT system ...
Epidermal stem cells in orthopaedic regenerative medicine.
(Multidisciplinary Digital Publishing Institute, 2013-05-31)
In the last decade, great advances have been made in epidermal stem cell studies at the cellular and molecular level. These studies reported various subpopulations and differentiations existing in the epidermal stem cell. ...
LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
(Nature Publishing Group, 2013-01-18)
Cells continuously sense and respond to external mechanical forces through their cytoskeleton. Here we show that only a small subset of actin fibers, those forming the perinuclear actin cap that wraps around the nucleus, ...
Time-varying wing-twist improves aerodynamic efficiency of forward flight in butterflies
(PLoS Organization, 2013-01-16)
Insect wings can undergo significant chordwise (camber) as well as spanwise (twist) deformation during flapping flight but the effect of these deformations is not well understood. The shape and size of butterfly wings leads ...
A multi-level system quality improvement intervention to reduce racial disparities in hypertension care and control: study protocol.
(BioMed Central, 2013-06-04)
Abstract
BACKGROUND:
Racial disparities in blood pressure control have been well documented in the United States. Research suggests that many factors contribute to this disparity, including barriers to care at ...
APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study
(PLoS Organization, 2013-05-22)
The interplay between the innate immune system restriction factor APOBEC3G and the HIV protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at least two ways: by inducing lethal mutations ...
Development of a screening tool to identify female survivors of gender-based violence in a humanitarian setting:qualitative evidence from research among refugees in Ethiopia.
(BioMed Central, 2013-06-12)
BACKGROUND:
High levels of gender-based violence (GBV) persist among conflict-affected populations and within humanitarian settings and are paralleled by under-reporting and low service utilization. Novel and evidence-based ...
Outbreak of H3N2 influenza at a US military base in Djibouti during the H1N1 pandemic of 2009.
(PLoS Organization, 2013-12-05)
BACKGROUND:
Influenza pandemics have significant operational impact on deployed military personnel working in areas throughout the world. The US Department of Defense global influenza-like illness (ILI) surveillance ...
Individual and contextual factors of influence on adherence to antiretrovirals among people attending public clinics in Rio de Janeiro, Brazil.
(BioMed Central, 2013-06-13)
BACKGROUND:
There are inconsistencies in the determinants of adherence to antiretrovirals (ARVs) across settings as well as a lack of studies that take into consideration factors beyond the individual level. This makes ...