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A multi-level system quality improvement intervention to reduce racial disparities in hypertension care and control: study protocol.
(BioMed Central, 2013-06-04)
Abstract
BACKGROUND:
Racial disparities in blood pressure control have been well documented in the United States. Research suggests that many factors contribute to this disparity, including barriers to care at ...
Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation.
(PLoS Organization, 2013-06-21)
Vascular endothelial growth factor (VEGF) signal transduction is central to angiogenesis in development and in pathological conditions such as cancer, retinopathy and ischemic diseases. However, no detailed mass-action ...
APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study
(PLoS Organization, 2013-05-22)
The interplay between the innate immune system restriction factor APOBEC3G and the HIV protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at least two ways: by inducing lethal mutations ...
CD36 and Fyn kinase mediate malaria-induced lung endothelial barrier dysfunction in mice infected with Plasmodium berghei.
(PLoS Organization, 2013-08-15)
Severe malaria can trigger acute lung injury characterized by pulmonary edema resulting from increased endothelial permeability. However, the mechanism through which lung fluid conductance is altered during malaria remains ...
Sexual and gender-based violence in areas of armed conflict: a systematic review of mental health and psychosocial support interventions.
(BioMed Central, 2013-08-05)
BACKGROUND:
Sexual and other forms of gender-based violence are common in conflict settings and are known risk factors for mental health and psychosocial wellbeing. We present findings from a systematic review of the ...
Individual and contextual factors of influence on adherence to antiretrovirals among people attending public clinics in Rio de Janeiro, Brazil.
(BioMed Central, 2013-06-13)
BACKGROUND:
There are inconsistencies in the determinants of adherence to antiretrovirals (ARVs) across settings as well as a lack of studies that take into consideration factors beyond the individual level. This makes ...
Longitudinal changes in intracardiac repolarization lability in patients with implantable cardioverter-defibrillator.
(Frontiers Research Foundation, 2013-08-12)
Background: While it is known that elevated baseline intracardiac repolarization lability is associated with the risk of fast ventricular tachycardia (FVT)/ventricular fibrillation (VF), the effect of its longitudinal ...
Triglyceride/HDL ratio as a screening tool for predicting success at reducing anti-diabetic medications following weight loss.
(PLoS Organization, 2013-07-15)
BACKGROUND AND OBJECTIVES:
Intentional weight loss, by reducing insulin resistance, results in both better glycemic control and decreased need for anti-diabetic medications. However, not everyone who is successful with ...
Morphological characterization of bushy cells and their inputs in the laboratory mouse (Mus musculus) anteroventral cochlear nucleus.
(PLoS Organization, 2013-08-26)
Spherical and globular bushy cells of the AVCN receive huge auditory nerve endings specialized for high fidelity neural transmission in response to acoustic events. Recent studies in mice and other rodent species suggest ...
A horizontal alignment tool for numerical trend discovery in sequence data: application to protein hydropathy.
(PLoS Organization, 2013-10-10)
An algorithm is presented that returns the optimal pairwise gapped alignment of two sets of signed numerical sequence values. One distinguishing feature of this algorithm is a flexible comparison engine (based on both ...