• Use of case reports and the Adverse Event Reporting System in systematic reviews: overcoming barriers to assess the link between Crohn's disease medications and hepatosplenic T-cell lymphoma 

  Selvaraj, Saranya A.; Chairez, Elizabeth; Wilson, Lisa M.; Lazarev, Mark; Bass, Eric B.; Hutfless, Susan (BioMed Central, 2013-07-05)

  BACKGROUND: To identify demographic and clinical characteristics associated with cases of hepatosplenic T-cell lymphoma (HSTCL) in patients with Crohn's disease, and to assess strength of evidence for a causal relationship ...

• Patient-reported assessment of functional gait outcomes following superior gluteal artery perforator reconstruction 

  Hur, Kevin; Ohkuma, Rika; Bellamy, Justin L.; Yamazaki, Michiyo; Manahan, Michele A.; Rad, Ariel N.; Cooney, Damon S.; Rosson, Gedge D. (American Society of Plastic Surgeons, 2013-08-14)

  BACKGROUND: Harvesting the superior gluteal artery perforator (SGAP) flap involves dissection of vessels through the gluteal muscle, potentially compromising gait and ambulation. We compared patient-reported gait and ...

• Positive effect of neurolysis on diabetic patients with compressed nerves of the lower extremities: a systematic review and meta-analysis 

  Baltodano, Pablo A.; Basdag, Basak; Bailey, Christopher R.; Baez, Marcelo J. Lacayo; Tong, Anne; Seal, Stella M.; Meléndez, Mark M.; Xie, Li; Manahan, Michele A.; Rosson, Gedge D. (American Society of Plastic Surgeons, 2013-07-02)

  BACKGROUND: Despite proven benefits of upper extremity nerve decompression in diabetics, neurolysis for diabetic patients with lower extremity (LE) nerve compression remains controversial. METHODS: A search of ...

• Increased flap weight and decreased perforator number predict fat necrosis in DIEP breast reconstruction 

  Mulvey, Carolyn L.; Cooney, Carisa M.; Daily, Francis F.; Colantuoni, Elizabeth; Ogbuago, Onyebuchi U.; Cooney, Damon S.; Rad, Ariel N.; Manahan, Michele A.; Rosson, Gedge D.; Sacks, Justin M. (American Society of Plastic Surgeons, 2013-05-28)

  BACKGROUND: Compromised perfusion in autologous breast reconstruction results in fat necrosis and flap loss. Increased flap weight with fewer perforator vessels may exacerbate imbalances in flap perfusion. We studied deep ...

• Preoperative anemia and postoperative outcomes in immediate breast reconstructive surgery : a critical analysis of 10,958 patients from the ACS-NSQIP database 

  Sarhane, Karim A.; Flores, José M.; Cooney, Carisa M.; Abreu, Francis M.; Lacayo, Marcelo; Baltodano, Pablo A.; Ibrahim, Zuhaib; Alrakan, Mohammed; Brandacher, Gerald; Rosson, Gedge D. (Plastic and reconstructive surgery. Global open., 2013-08-06)

  Background: Preoperative anemia is independently associated with adverse outcomes after general and cardiac surgery. Outcomes after breast reconstruction are not established. We assessed the effect of preoperative ...

• A multi-level system quality improvement intervention to reduce racial disparities in hypertension care and control: study protocol. 

  Cooper, Lisa A; Marsteller, Jill A.; Noronha, Gary J.; Flynn, Sarah J.; Carson, Kathryn A.; Boonyasai, Romsai T.; Anderson, Cheryl A.; Aboumatar, Hanan J.; Roter, Debra L.; Dietz, Katherine B.; Miller, Edgar R III; Prokopowicz, Gregory P.; Dalcin, Arlene T.; Charleston, Jeanne B.; Simmons, Michelle; Huizinga, Mary Margaret (BioMed Central, 2013-06-04)

  Abstract BACKGROUND: Racial disparities in blood pressure control have been well documented in the United States. Research suggests that many factors contribute to this disparity, including barriers to care at ...

• Individual and contextual factors of influence on adherence to antiretrovirals among people attending public clinics in Rio de Janeiro, Brazil. 

  Hanif, Homaira; Bastos, Francisco Inácio; Malta, Monica; Bertoni, Neilane; Surkan, Pamela J.; Winch, Peter J.; Kerrigan, Deanna (BioMed Central, 2013-06-13)

  BACKGROUND: There are inconsistencies in the determinants of adherence to antiretrovirals (ARVs) across settings as well as a lack of studies that take into consideration factors beyond the individual level. This makes ...

• Development of a screening tool to identify female survivors of gender-based violence in a humanitarian setting:qualitative evidence from research among refugees in Ethiopia. 

  Wirtz, Andrea L; Glass, Nancy; Pham, Kiemanh; Aberra, Amsale; Rubenstein, Leonard S.; Singh, Sonal; Vu, Alexander (BioMed Central, 2013-06-12)

  BACKGROUND: High levels of gender-based violence (GBV) persist among conflict-affected populations and within humanitarian settings and are paralleled by under-reporting and low service utilization. Novel and evidence-based ...

• ClinicalTrials.gov registration can supplement information in abstracts for systematic reviews: a comparisonstudy. 

  Scherer, Roberta W.; Huynh, Lynn; Ervin, Ann Margret; Taylor, Jakeisha; Dickersin, Kay (BioMed Central, 2013-06-18)

  BACKGROUND: The inclusion of randomized controlled trials (RCTs) reported in conference abstracts in systematic reviews is controversial, partly because study design information and risk of bias is often not fully ...

• Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen. 

  Mao, Hui; Kano, Gen; Hudson, Sherry A.; Brummet, Mary; Zimmermann, Nives; Zhu, Zhou; Bochner, Bruce S. (PLoS Organization, 2013-06-28)

  Abstract BACKGROUND: Siglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas Siglec-8 mediated death involves caspases and/or ...

• A Particle Model for Prediction of Cement Infiltration of Cancellous Bone in Osteoporotic Bone Augmentation. 

  Basafa, Ehsan; Murphy, Ryan J.; Kutzer, Michael D.; Otake, Yoshito; Armand, Mehran (PLoS Organization, 2013-06-26)

  Femoroplasty is a potential preventive treatment for osteoporotic hip fractures. It involves augmenting mechanical properties of the femur by injecting Polymethylmethacrylate (PMMA) bone cement. To reduce the risks involved ...

• Outbreak of H3N2 influenza at a US military base in Djibouti during the H1N1 pandemic of 2009. 

  Cosby, Michael T.; Pimentel, Guillermo; Nevin, Remington L.; Ahmed, Salwa Fouad; Klena, John D.; Amir, Ehab; Younan, Mary; Browning, Robert; Sebeny, Peter J. (PLoS Organization, 2013-12-05)

  BACKGROUND: Influenza pandemics have significant operational impact on deployed military personnel working in areas throughout the world. The US Department of Defense global influenza-like illness (ILI) surveillance ...

• Pulmonary Tuberculosis Incidence and Risk Factors in Rural Areas of China: A Cohort Study 

  Chen, Wei; Shu, Wen; Wang, Min; Hou, Yongchun; Xia, Yinyin; Xu, Weiguo; Bai, Liqiong; Nie, Shaofa; Cheng, Shiming; Xu, Yihua (PLoS Organization, 2013-03-12)

  The incidence of tuberculosis (TB) and its risk factors in China remains unclear. This study examined TB incidence and relative risk factors in rural areas of China. Participants (n = 177,529) were recruited in Xiangtan ...

• Multiple Consequences of a Single Amino Acid Pathogenic RTK Mutation: The A391E Mutation in FGFR3 

  Chen, Fenghao; Sarabipour, Sarvenaz; Hristova, Kalina (PLoS Organization, 2013-02-20)

  The A391E mutation in fibroblast growth factor receptor 3 (FGFR3) is the genetic cause for Crouzon syndrome with Acanthosis Nigricans. Here we investigate the effect of this mutation on FGFR3 activation in HEK 293 T cells ...

• APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study 

  Mac Gabhann, Feilim; Hosseini, Iraj (PLoS Organization, 2013-05-22)

  The interplay between the innate immune system restriction factor APOBEC3G and the HIV protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at least two ways: by inducing lethal mutations ...

• Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence. 

  He, Lijuan; Hristova, Kalina (Nature Publishing Group, 2012-11-14)

  EGFR is the best studied receptor tyrosine kinase. Yet, a comprehensive mechanistic understanding of EGFR signaling is lacking, despite very active research in the field. In this paper, we investigate the role of the ...

• Role of exhaled nitric oxide as a predictor of atopy. 

  Romero, Karina M.; Robinson, Colin L.; Baumann, Lauren M.; Gilman, Robert H.; Hamilton, Robert G.; Hansel, Nadia N; Checkley, William; PURA Study Investigators (BioMed Central, 2013-05-02)

  BACKGROUND: The fractional exhaled nitric oxide (FeNO) is a quantitative, noninvasive and safe measure of airways inflammation that may complement the assessment of asthma. Elevations of FeNO have recently been found ...

• Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer. 

  Bender, R. Joseph; Mac Gabhann, Feilim (PLoS Organizaton, 2013-05-08)

  Triple negative breast cancers (TNBC) are difficult to treat due to a lack of targets and heterogeneity. Inhibition of angiogenesis is a promising therapeutic strategy, but has had limited effectiveness so far in breast ...

• Characterizing optical properties of nano contrast agents by using cross-referencing OCT imaging. 

  Xi, Jiefeng; Chen, Yongping; Li, Xingde (Optical Society of America, 2013-05-09)

  We report a cross-referencing method to quickly and accurately characterize the optical properties of nanoparticles including the extinction, scattering, absorption and backscattering cross sections by using an OCT system ...

• Epidermal stem cells in orthopaedic regenerative medicine. 

  Li, Jin; Zhen, Gehua; Tsai, Shin-Yi; Jia, Xiaofeng (Multidisciplinary Digital Publishing Institute, 2013-05-31)

  In the last decade, great advances have been made in epidermal stem cell studies at the cellular and molecular level. These studies reported various subpopulations and differentiations existing in the epidermal stem cell. ...

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