JHU Open Access Research
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This collection contains research from scholars across all the schools at The Johns Hopkins University
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Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies
OBJECTIVE: Endocrine therapy is often considered as a treatment for hormone-responsive gynecologic malignancies. In breast cancer, activating mutations in the estrogen receptor (mutESR1) contribute to therapeutic resistance ... -
Does volunteer community health work empower women? Evidence from Ethiopia’s Women’s Development Army
Abstract Of the millions of Community Health Workers (CHWs) serving their communities across the world, there are approximately twice as many female CHWs as there are male. Hiring women has in many cases ... -
Laissez-Faire
(John Wiley & Sons, 2015) -
New Directions, Then and Now
(Oxford University Press, 2017) -
The Reinvention of Entrepreneurship
(Cornell University Press, 2018) -
THE RADICAL CONSERVATISM OF FRANK H. KNIGHT
This article examines the most prominent interwar economist at the University of Chicago, Frank Knight, through the lens of a controversial 1932 lecture in which he exhorted his audience to vote Communist. The fact that ... -
Conspicuous by Its Absence: Diagnostic Expert Testing under Uncertainty
We study the problem a diagnostic expert (e.g., a physician) faces when offering a diagnosis to a client (e.g., a patient) that may be based only on her own diagnostic ability or supplemented by a diagnostic test—conventional ... -
Biomaterials as vectors for the delivery of CRISPR–Cas9
The emergence of the CRISPR–Cas9 gene editing system has generated considerable hope and excitement in the field of gene therapy and the larger scientific community. Recently, biomaterials have become an attractive option ... -
Co-opetition in Service Clusters with Waiting-Area Entertainment
Problem Definition: Unoccupied waiting feels longer than it actually is. Service providers operationalize this psychological principle by offering entertainment options in waiting areas. A service cluster with a common ... -
Salesforce Contracting under Uncertain Demand and Supply: Double Moral Hazard and Optimality of Smooth Contracts
We consider the compensation design problem of a firm that hires a salesperson to exert effort to increase demand. We assume both demand and supply to be uncertain, with sales being the smaller of demand and supply, and ... -
Community health workers and accountability: reflections from an international “think-in”
Community health workers (CHWs) are frequently put forward as a remedy for lack of health system capacity, including challenges associated with health service coverage and with low community engagement in the health system, ... -
Polio Eradication and Health Systems in Karachi: Vaccine Refusals in Context
Community and health worker engagement will be key to polio eradication in Karachi, Pakistan. In this study, the authors conducted participant observation, interviews, and a document review in SITE Town, Karachi, an area ...
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