JHU Open Access Research
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This collection contains research from scholars across all the schools at The Johns Hopkins University
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Mouse PVRIG Has CD8+ T Cell–Specific Coinhibitory Functions and Dampens Antitumor Immunity
A limitation to antitumor immunity is the dysfunction of T cells in the tumor microenvironment, in part due to upregulation of coinhibitory receptors such as PD-1. Here, we describe that poliovirus receptor-related ... -
Economic Benefits of Immunization for 10 Pathogens in 94 Low- and Middle-Income Countries From 2011 to 2030 Using Cost-of-Illness and Value-of-Statistical-Life Approaches
Objectives Vaccination has prevented millions of deaths and cases of disease in low- and middle-income countries (LMICs). During the Decade of Vaccines (2011-2020), international organizations, including the World Health ... -
The anthropology of health systems: A history and review
Ethnographies of health systems are a theoretically rich and rapidly growing area within medical anthropology. Critical ethnographic work dating back to the 1950s has taken policymakers and health staff as points of entry ... -
Acute Tubular Injury in a Woman with Placental Abruption
Here we report the case of a young woman who developed acute renal failure following prolonged cesarean section delivery. The surgical procedure was complicated by placental abruption and uterine leiomyomata. A kidney ... -
The Panorama of Cancer Genetics
Cancer, a disease of the genome, is caused by a combination of germline predisposing variants and acquired somatic mutations. A unified view of heritable and acquired genetic factors will improve our understanding of cancer ... -
Codifying Credit: Everyday Contracting and the Spread of the Civil Code in Nineteenth-Century Mexico
<jats:p>Between the 1870s and the 1910s, municipal court officials in southernmost Mexico recorded contracts regarding small debts and credits in what they labeled libros de conocimientos. While only very rarely citing ... -
Assessment of Online Resources for Returning to School During and After Treatment of Childhood Cancer
Objective: To evaluate current online parent education resources for children returning to school after a cancer diagnosis. Methods: Online search was conducted using 3 search engines and terms recommended by affected ... -
The Corruption Game: Health Systems, International Agencies, and the State in South Asia
Drawing on ethnographic material collected in Pakistan, India, and Nepal, this article analyzes patterns of corruption in vaccination programs in South Asia. Corrupt practices—which required substantial work—were deeply ... -
Health Organizational Design: Information Exchange and Accountability
(Wiley StatsRef: Statistics Reference Online, 2020-05-16)In this article, we introduce two essential components of the field of healthcare organizational design: information exchange and accountability. We emphasize how the limitations from information-exchange and accountability ... -
External Societal Costs of Antimicrobial Resistance in Humans Attributable to Antimicrobial Use in Livestock
Antimicrobial use (AMU) in animal agriculture contributes to antimicrobial resistance (AMR) in humans, which imposes significant health and economic costs on society. Economists call these costs negative externalities, ... -
Incentive Design for Operations-Marketing Multitasking
A firm hires an agent (e.g., store manager) to undertake both operational and marketing tasks. Marketing tasks boost demand, but for demand to translate into sales, operational effort is required to maintain adequate ... -
High Coping Self-Efficacy Associated With Lower Sweat Inflammatory Cytokines in Adults: A Pilot Study
Introduction/Background: Chronic diseases, like diabetes and heart disease, are considered inflammatory conditions with elevated levels of the proinflammatory cytokines interleukin-6 (IL-6) and tumor necrosis factor alpha ... -
Market Politics in an Age of Automation
(University of Pennsylvania Press, 2019) -
Heart Analytics: Analytical Modeling of Cardiovascular Care
Cardiovascular diseases (CVDs) are the leading cause of death and disability both in the United States and worldwide. Despite high morbidity, mortality, and cost in the US and global healthcare systems, cardiovascular care ...
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