Browsing Theses and Dissertations, Electronic (ETDs) by Title
Now showing items 4568-4587 of 6498
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Quality assurance using outlier detection for automatic segmentation of cerebellar peduncles
(Johns Hopkins UniversityUSA, 2015-08-14)Cerebellar peduncles (CPs) are white matter tracts that connect the cerebellum to other brain regions. Automatic segmentation and quantification methods of the CPs are important for objectively and efficiently studying ... -
QUALITY ASSURANCE USING OUTLIER DETECTIONS FOR CEREBELLAR LOBULE SEGMENTATION
(Johns Hopkins UniversityUSA, 2018-05-09)The cerebellum plays an important role in motor control and cognitive activities. In recent years, several methods have been proposed for automatic cerebellum parcellation. Usually, the segmentation accuracy is evaluated ... -
Quality control under stress: Ubiquilin 2 bridges protein and RNA homeostasis at stress granules in ALS/FTD pathology
(Johns Hopkins UniversityUSA, 2019-02-04)Both protein and RNA quality control are critical for cell survival during stress and are disrupted in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS is the most ... -
QUALITY OF ANTENATAL CARE SERVICES IN LOW-INCOME COUNTRIES: INVESTIGATING ITS MEANING AND MEASUREMENT
(Johns Hopkins UniversityUSA, 2019-01-17)Background: Measuring quality of maternal health services is a fundamental step toward enhancing our understanding of how to improve maternal health outcomes; yet comprehensive quality of care measures are limited. This ... -
Quantification Learning with Applications to Mortality Surveillance
(Johns Hopkins UniversityUSA, 2020-04-06)\chapter*{Abstract} This thesis is motivated by estimating the cause specific mortality fraction (CSMF) for children deaths in Mozambique. In countries where many deaths are not assigned a cause of death, CSMF estimation ... -
QUANTIFICATION OF CORONARY FLOW VELOCITY VIA CONTRAST DISPERSION PATTERNS: INSIGHTS FROM COMPUTATIONAL MODELING AND COMPUTED TOMOGRAPHY EXPERIMENTS
(Johns Hopkins UniversityUSA, 2016-07-11)Advances in multi-detector cardiac computed tomography (CT) have expanded its use beyond coronary atherosclerosis to a suite of functional myocardial imaging options that now closely parallels magnetic resonance imaging; ... -
Quantifying Cardiac Microstructure Using Automated Two-Photon Microscopy
(Johns Hopkins UniversityUSA, 2014-05-09)Two-photon fluorescence microscopy is a three-dimensional imaging technology based on the nonlinear excitation of fluorophores. It has been widely used to map the 3D pattern of neuronal connections in the brain, and for ... -
Quantifying Human Mobility Using The Longest Distance Traveled
(Johns Hopkins University, 2014-04-25)Background: Population movement has a dramatic impact on infectious disease epidemiology. Human mobility data is increasingly being used to model pathogen dispersion, but it is difficult to study long-distance movement of ... -
Quantifying Nutrient and Sediment Export from the Chesapeake Bay Watershed: Retrospective Analyses and Method Improvements
(Johns Hopkins UniversityUSA, 2016-07-18)Toward Chesapeake Bay restoration, management programs have focused for decades on reducing nutrient and sediment loadings from the Chesapeake Bay watershed (CBW). To assess progress and shape future strategies, a critical ... -
QUANTIFYING OLDER BLACK AMERICANS’ EXPOSURE TO STRUCTURAL RACIAL DISCRIMINATION: A MIXED METHODS INSTRUMENT DESIGN STUDY
(Johns Hopkins UniversityUSA, 2021-06-21)Background: Racism and racial discrimination are fundamental causes of health disparities. Exposure to racial discrimination is typically assessed using self-report measures or using indicators of residential segregation. ... -
Quantifying Relationships Between Storage and Discharge in a Large Database of Reference Watersheds Across the Continental US
(Johns Hopkins University, 2015-04-24)So far there is not a globally known system for catchment classification that will aid in improved models and communication amongst hydrologists. This paper combines two common methods used to analyze the hydrologic response ... -
Quantifying RTK Signal Transduction Processes Across The Plasma Membrane
(Johns Hopkins UniversityUSA, 2022-01-10)The signal transduction process across the plasma membrane is a critically important step in cell signaling. However, our understanding of this process is incomplete and a robust method to quantitatively measure this process ... -
Quantifying the Association between Objectively-Measured Physical Activity and Current or Future Multiple Sclerosis Status in the UK Biobank
(Johns Hopkins UniversityUSA, 2022-05-03)Background: Objectively measured physical activity (PA) data were collected in the accelerometry sub-study of the UK Biobank. The association between PA and multiple sclerosis (MS) is studied. Objectives: (1) Compare and ... -
Quantifying the difference in activity between diabetics and healthy controls using activity data measured by accelerometers
(Johns Hopkins UniversityUSA, 2018-04-27)The National Health and Nutrition Examination Survey (NHANES) is a com- bination of multiple cross-sectional studies designed to be representative for the US population. In addition to standard demographic, environmental ... -
Quantifying the Indirect Effects of Haemophilus Influenzae type b Vaccination in Children Under 5 Years-Old
(Johns Hopkins University, 2015-05-01)Background Haemophilus influenzae type b (Hib) is a significant cause of meningitis and pneumonia among children under 5 years. A conjugate vaccine has been available since the mid-1980s, leading to disease reductions well ... -
Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution
(Johns Hopkins UniversityUSA, 2022-02-03)Vascularization is critical for skull development, maintenance, and healing. Yet, there remains a significant knowledge gap in the relationship of blood vessels to cranial skeletal progenitors during these processes. One ... -
QUANTITATIVE ANALYSIS OF THE HISTONE LOCUS BODY IN SUMO KNOCKOUT HUMAN CELLS
(Johns Hopkins UniversityUSA, 2021-05-03)Small ubiquitin-related modifiers (SUMOs) are proteins that can be reversibly conjugated to many other cellular proteins. Mammalian cells express up to five SUMO paralogs and our lab has recently generated paralog-specific ... -
A QUANTITATIVE ANALYSIS OF THE RELATIONSHIPS BETWEEN POLITICAL BEHAVIORS AND AGGREGATED ELECTORAL RESULTS IN THE U.S. HOUSE OF REPRESENTATIVES, 1968-2010
(Johns Hopkins University, 2015-07-01)This thesis uses quantitative methods to analyze the relationships between incumbent electoral results in the U.S. House of Representatives between 1968 and 2010 and various political behaviors including legislative ... -
A Quantitative Approach to Military Water System Vulnerability Assessments
(Johns Hopkins University, 2014-05-09)The Department of the Army routinely conducts water system vulnerability assessment (WSVA) on military water distribution systems (WDS). Risk assessors construct attack scenarios and then estimate the risks using their ... -
QUANTITATIVE ASSESSMENT OF CELL TYPE IDENTITY ACROSS PLATFORMS AND ACROSS SPECIES WITH APPLICATIONS TO STEM CELL ENGINEERING AND OSTEOSARCOMA
(Johns Hopkins UniversityUSA, 2021-02-03)Single-cell RNA-seq (scRNA-seq) has emerged as a powerful tool in diverse applications. A near-universal step in the analysis of scRNA-seq data is to hypothesize the identity of each cell. Often, this is achieved by manually ...