Browsing Theses and Dissertations, Electronic (ETDs) by Title
Now showing items 1276-1295 of 6070
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D1 AND D2 DOPAMINE RECEPTOR BIASED AND HETEROMERIC SIGNALING: IMPLICATIONS FOR PROTEIN CONFORMATIONAL FLUIDITY
(Johns Hopkins UniversityUSA, 2015-08-24)The D1R and D2R dopamine receptor (DAR) subtypes represent the two most abundant and highly targeted DARs, but the precise mechanisms of drug action at the molecular level are not well understood. A revolution in the ... -
DARK NOISE AND THE APO-OPSIN EFFECT IN RETINAL RODS AND CONES
(Johns Hopkins UniversityUSA, 2018-11-01)Our visual system is exceedingly complex, but initiating light detection requires only a small number of reactions in retinal rods and cones. In the first stages of vision, the exact nature of signal amplification and ... -
Dark Z' Search and (Un)Natural Supersymmetric Models
(Johns Hopkins University, 2014-08-26)The Standard Model (SM) of particle physics is the most successful theory of particles and fundamental laws of nature. It has been tested numerous times for over forty years. Yet, it is considered to be incomplete. It does ... -
DATA ACQUISITION BOARD FOR STROKE REHABILITATION HAND DEVICE
(Johns Hopkins UniversityUSA, 2018-02-26)Individuals with weakened upper limbs from stroke-related incidents need early rehabilitation with accurate tools and engaging applications to improve patient outcomes. In an effort to enhance a pre-existing version of a ... -
Data Fusion at Scale in Astronomy
(Johns Hopkins UniversityUSA, 2017-10-26)We have arrived in an era where we face a deluge of data streaming in from countless sources and across virtually all disciplines; This holds especially true for data intensive sciences such as astronomy where upcoming ... -
Data Fusion via Manifold Matching
(Johns Hopkins University, 2013-10-23)Data fusion has been an interesting and challenging research topic, which receives intensive investigation in many areas. The theory and practice of data fusion - the integration of information from disparate sources - are ... -
DATA REDUCTION FOR THE CLASS EXPERIMENT AND LIMITS ON SPECTRAL INDEX VARIATIONS IN THE POLARIZED DUST FOREGROUND
(Johns Hopkins UniversityUSA, 2021-08-16)One of the major goals in cosmology today is the detection of primordial gravitational waves in the Cosmic Microwave Background (CMB) polarization. This detection would be a confirmation of inflation and significantly tighten ... -
DATA-DRIVEN AND KNOWLEDGE-DRIVEN COMPUTATIONAL MODELS OF ANGIOGENESIS IN APPLICATION TO PERIPHERAL ARTERIAL DISEASE
(Johns Hopkins University, 2015-03-24)Angiogenesis, the formation of new blood vessels from pre-existing vessels, is involved in both physiological conditions (e.g. development, wound healing and exercise) and diseases (e.g. cancer, age-related macular ... -
Data-Driven Assessment of Chinese Economic Influence
(Johns Hopkins UniversityUSA, 2020-05-18)In recent years, China has engaged in a long-term effort to erode US dominance in critical industries and thereby undermine US influence in important world regions. If unaddressed, this could result in a future in which ... -
Data-Driven Representation, Learning and Applications: From Compressed Sensing to Deep Neural Networks
(Johns Hopkins UniversityUSA, 2017-10-23)As the development of high-density sensors, the compressed sensing (CS) and sparse representation have been successfully implemented for building power-efficient systems by reducing sampling, transmission bandwidth and ... -
DE NOVO ENGINEERING OF CHEMOTACTIC TRANSDUCTION IN CELLS & CELL-MIMETIC DEVICES
(Johns Hopkins UniversityUSA, 2018-03-27)Spatiotemporal regulation of signaling is an integral feature of biologicalnetworks. Cellular processes driven by membrane-localized forces are prevalentand crucial in both health and disease. These include cell division, ... -
De novo genome assembly and analysis of non-allelic recombination in pathogenic yeast Candida glabrata
(Johns Hopkins UniversityUSA, 2019-12-02)Candida glabrata is an opportunistic pathogen in humans, responsible for approximately 20% of disseminated candidiasis. C. glabrata’s ability to adhere to host tissue is mediated by GPI-anchored cell wall proteins (GPI-CWPs); ... -
DEA VIRTUS: MARTIAL GLORY AS DIVINITY IN THE LITERARY AND VISUAL CULTURE OF ANCIENT ROME
(Johns Hopkins UniversityUSA, 2020-10-29)The Roman goddess Virtus has long been enshrouded in mystery from her cult to her image. Originally an ethical quality meaning “manliness,” virtus was deified during the Republic by the general Marcellus, who vowed to ... -
Dead Time In America: An Evaluation of the Early Stages of Judicial Processing
(Johns Hopkins UniversityUSA, 2018-09-21)This study will seek to reveal problems within the judicial process that have led to gross amounts of people being detained between arrest and the adjudication of their case. The nickname of dead time has been given to the ... -
DEAR LANDLORD: HOW THE OWNERSHIP AND MANAGEMNT OF RENTAL PROPERTIES IN BALTIMORE, DALLAS, AND CLEVELAND MATTER FOR TENANTS, NEIGHBORHOODS, AND THE CITY
(Johns Hopkins UniversityUSA, 2018-07-06)The strategies, resources, choices, ideologies, and identities of rental property owners are of enormous consequence for poor families and urban development. While frequently studied in the aggregate, little research has ... -
Decamerons Without Women: The Spiritualization of Italian Literature in the Sixteenth and Seventeenth Centuries
(Johns Hopkins UniversityUSA, 2017-05-02)This dissertation takes Francesco Dionigi da Fano’s 1594 Decamerone Spirituale as the prime example of the many ‘spiritualizations’ of classics of Italian literature in the sixteenth and seventeenth centuries. The author, ... -
Decentralized Anonymous Payments
(Johns Hopkins UniversityUSA, 2017-08-31)Decentralized payment systems such as Bitcoin record monetary transactions between pseudonyms in an append-only ledger known as a blockchain. Because the ledger is public, permanent, and readable by anyone, a user’s privacy ... -
Decentralized Renewable Energy Efforts in Rural India
(Johns Hopkins UniversityUSA, 2021-05-17)This paper examines India’s progress with decentralized renewable energy (DRE) throughout its rural regions. It looks at various programs implemented in India to gauge whether the country’s efforts are sufficient to meet ... -
DECIPHERING GENETICS OF GENE EXPRESSION AND CHROMATIN ACCESSIBILITY VIA INTEGRATION OF LARGE-SCALE GENOMIC DATA
(Johns Hopkins UniversityUSA, 2021-07-26)Understanding the impact of genetic mutations on complex phenotypes is essential towards understanding human phenotypes including diseases. Capturing the genetic regulation on gene expression and on epigenetic signatures ... -
Deciphering Intracellular Signaling Regulating Directed Cell Migration
(Johns Hopkins University, 2013-10-18)Directed cell migration is a ubiquitous phenomenon with implications in development, wound healing, immunity, and metastasis. The ability of cells to orient their migration is dependent on the presence of external cues, ...