Now showing items 1-6 of 6
ALV INDUCED TUMORIGENESIS: Identifying Clonal Progression of Tumors and Novel Cancer Associated Genes
(Johns Hopkins University, 2017-12-20)
Avian leukosis virus (ALV) is a simple retrovirus that infects and causes cancer in chickens. The virus integrates into the chicken genome and it can alter the expression of surrounding genes via its strong promoter and ...
Development of cancer biomarker assays from dna in various bodily fluids
(Johns Hopkins University, 2017-05-18)
Abstract DNA from cancer cells can enter surrounding fluid after apoptosis or necrosis. This DNA can be identified by sampling and sequencing the fluid looking for the mutations that gave rise to the cancer, referred to ...
Radio-morphology: Parametric Shape-Based Features in Radiotherapy
(Johns Hopkins University, 2017-12-18)
In radiotherapy, it is necessary to characterize dose over the patient anatomy to target areas and organs at risk. Current tools provide methods to describe dose in terms of percentage of volume and magnitude of dose, but ...
Simulation Based Strategies for Clinical Translation of Magnetic Nanoparticle Hyperthermia
(Johns Hopkins University, 2017-09-29)
Magnetic nanoparticles have gained significant importance in the recent past for their use in biomedical applications such as drug delivery, imaging, diagnosis, and therapy. Magnetic nanoparticle hyperthermia is the selective ...
An Exploration of the Role of Family Members in Pre-Surgical Visits
(Johns Hopkins University, 2017-07-11)
There were 46 visits (75%) in which companions were present, and 15 (25%) in which companions were not present.
Novel Methods of Targeting Protein Cytotoxins to Metastatic Prostate Tumors: Teaching "Old Proteins" New Tricks
(Johns Hopkins University, 2017-03-21)
Prostate cancer is among the leading causes of cancer-related death in the United States with 30,000 people succumbing to the disease every year. A vast majority of these men, at the time of diagnosis, presented with distal ...