Now showing items 1-4 of 4
AN ANALYSIS OF RIBOSOME E-SITE BINDING PROTEINS AND THEIR FUNCTIONS IN TRANSLATION ELONGATION AND TERMINATION
(Johns Hopkins University, 2017-10-17)
During translation, the ribosome uses substrate aminoacyl-tRNAs in concert with many protein factors to synthesize the protein encoded by a particular mRNA. Substrate tRNAs can bind inside the ribosome in three unique ...
Role of eIF4A in mRNA recruitment to the initiating ribosome
(Johns Hopkins University, 2017-05-03)
Control of protein synthesis is a fundamental process necessary for life and energetically one of the most expensive phases of gene expression. The majority of translational control takes place during the initiation step. ...
Synonymous codons affect polysome spacing, protein production and protein folding stress: studies of bacterial translation using ribosome profiling
(Johns Hopkins University, 2017-07-19)
The acquisition of protein secondary and tertiary structure depends on the primary sequence of amino acids. However, predicting a protein's folded structure is difficult even with the knowledge of its sequence. It has been ...
THE REGULATION OF HYPOXIC ADAPTATION THROUGH COUPLED PROLYL DIHYDROXYLATION AND NUCLEAR IMPORT OF PRE-RIBOSOMAL uS12/RPS23 IN FISSION YEAST
(Johns Hopkins University, 2017-07-18)
Oxygen and lipid homeostases require the sterol regulatory element-binding protein (Sre1) in Schizosaccharomyces pombe. Sre1 is cleaved to release the N-terminal basic helix-loop-helix (bHLH) transcription factor Sre1N ...