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Elucidating differences in the conformational dynamics of K-Ras isoforms
(Johns Hopkins University, 2015-05-15)
Humans ubiquitously express three genes (HRAS, KRAS, and NRAS) that encode four different isoforms of Ras, an integral p21 GTPase acting as an effector of cell surface receptors and regulating cell survival, proliferation, ...