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Characterization of Poly(ADP-ribose) (PAR) as a death signal in PARP-1 dependent cell death
(Johns Hopkins University, 2015-05-08)
Poly(ADP-ribose)polymerase (PARP) overactivation induces cell death called parthanatos via production of large swells of PAR. Parthanatos is apparent in debilitating diseases such as stroke and Parkinson’s disease. PAR is ...
The Development of Nanofiber Hydrogel Composite Microparticles and Mesenchymal Stem Cell Delivery for Myocardial Infarction Repair.
(Johns Hopkins University, 2021-05-24)
The delivery of mesenchymal stem cells using biomaterial scaffolds to improve regenerative outcomes provides exciting opportunities for managing tissue damage and functional recovery after a myocardial infarction event. ...