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CHARACTERIZATION OF THE UNMYELINATED TYPE II AFFERENTS AS COCHLEAR NOCICEPTORS
(Johns Hopkins University, 2016-03-22)
In the mammalian cochlea, acoustic information is carried to the brain by the predominant (95%) large diameter, myelinated type I afferents, each of which is postsynaptic to a single inner hair cell. The remaining thin, ...
Feedback interconnection based input-output analysis of spatio-temporal response in wall-bounded shear flows
(Johns Hopkins University, 2021-07-14)
This work investigates the characteristic length, time, and velocity scales in canonical wall-bounded shear flows through analysis of their spatio-temporal frequency response operators. First, we employ input-output analysis ...
Dendrimer-based Delivery of Peptides and Antibodies for Choroidal Neovascularization
(Johns Hopkins University, 2022-12-02)
Biomolecular drugs are the cornerstone of modern medicine, but their indiscriminate targeting of broad biological processes has devastating effects on disease treatment and quality of life. Biologics are a relatively new ...