Search
Now showing items 1-10 of 733
VISUALIZING MUSCULAR AND SKELETAL ANOMALIES OF A TRISOMY 18 CYCLOPIC HUMAN FETUS IN AN EVO-DEVO CONTEXT WITH TRISOMY COMPARISON
(Johns Hopkins University, 2014-03-26)
The study of abnormal development, such as trisomy syndromes, allows us to explore the mysteries and mechanisms of normal evolutionary/developmental (evo/devo) processes, and provides insight into how morphology changes ...
Exposure to ambient air pollution as a potential explanation of ethnic disparities in atherosclerosis severity and progression
(Johns Hopkins University, 2013-09-12)
Disparities in atherosclerosis and other cardiovascular outcomes by race/ethnicity persist in the United States even after accounting for clinical risk factors. Exposure to ambient air pollution, which is associated with ...
Robust Anomaly Detection with Applications to Acoustics and Graphs
(Johns Hopkins University, 2014-02-06)
Our goal is to develop a robust anomaly detector that can be incorporated into pattern recognition systems that may need to learn, but will never be shunned for making egregious errors. The ability to know what we do not ...
Interrogating the Human CD8+ T Cell Response in HCV Infection
(Johns Hopkins University, 2014-03-20)
Hepatitis C virus (HCV) infects nearly 170 million individuals worldwide and remains one of the leading causes of cirrhosis and hepatocellular carcinoma. Approximately 15-20% of individuals will spontaneously clear the ...
Grid-based Finite Elements System for Solving Laplace-Beltrami Equations on 2-Manifolds
(Johns Hopkins University, 2013-10-25)
Solving the Poisson equation has numerous important applications. On a Riemannian 2-manifold, the task is most often formulated in terms of finite elements and two challenges commonly arise: discretizing the space of ...
Dextran-Allyl Isocyanate-Ethylamine Hydrogel for Treating Third-Degree Dermal Burn Wounds
(Johns Hopkins University, 2014-05-01)
Third-degree burn wound is characterized by the full-thickness injury of the skin, including both the epidermal and the dermal layer. These wounds do not heal spontaneously and require excision of the necrotic tissue. ...
Elucidating the role of Keratin 17 in cervical carcinogenesis
(Johns Hopkins University, 2014-06-26)
Cervical malignancies develop when viral genes from high-risk strains of the Human Papilloma Virus (HPV) such as HPV type 16 and 18 are expressed in the cervical epithelium. Expression of Keratin 17 (K17), an intermediate ...
Understanding the Sino-Japanese Bilateral Relationship
(Johns Hopkins University, 2014-12-30)
This thesis portfolio assesses the Sino-Japanese bilateral relationship using three sources of contention. The main question is, “What are the main sources of conflict in the Sino-Japanese bilateral relationship?” Each ...
Investigating Alternative Methods of Nucleic Acid Delivery in Oocytes
(Johns Hopkins University, 2014-07-01)
Studies using RNA interference in oocytes have elucidated processes relating to oocyte function and fertilization. Currently, the only viable method for genetic manipulation of oocytes is microinjection, a very time consuming ...
EVALUATION OF THE PROTECTIVE EFFICACY OF HIV-1 PROTEASE INHIBITORS AGAINST ENTEROVIRUS 71 INFECTION IN VITRO
(Johns Hopkins University, 2014-04-26)
Enterovirus associated hand, foot and mouth disease continues to be a prominent public health issue despite the numerous vaccine trials and drug development attempts. The lack of a specific and protective antiviral drug ...