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REGULATION OF INNATE VIRAL SENSING AND CHRONIC INFLAMMATION
(Johns Hopkins University, 2016-09-01)
Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are chronic viral infections that affect hundreds of millions of individuals worldwide. Despite significant advancements in treatment, increasing evidence ...
EFFECTS OF INTIMATE PARTNER VIOLENCE AND MENTAL HEALTH ON HIV DISEASE PROGRESSION IN WOMEN
(Johns Hopkins University, 2016-08-08)
Background: Intimate partner violence (IPV) has the ability to negatively impact the lives of women living with HIV through decreased adherence, increased mental health symptoms and substance use and through physiologic ...
Intersectional disparities in HIV testing among male youth in the U.S.
(Johns Hopkins University, 2016-10-27)
Background: HIV testing remains a significant public health problem, particularly for adolescents who are the fastest growing age group of those infected with HIV. Data on HIV testing among adolescents is more limited and ...
Attacking the HIV Epidemic From All Sides: Optimization of PCR Strategies to Measure Clonal Expansion and Quantitative Evaluation of Dolutegravir
(Johns Hopkins University, 2016-06-16)
Although great progress has been achieved in the fight against HIV and AIDS, an epidemic continues to rage worldwide. Alongside public health and clinical efforts, scientific research plays a major role in this fight; ...
HIV risk in partners of migrants and residents in Rakai, Uganda: an observational cohort study
(Johns Hopkins University, 2018-04-27)
Background: Migration status has been linked to a higher burden of untreated HIV infection throughout sub-Saharan Africa. In Rakai District, Uganda, we have previously shown that migrants have an increased risk of HIV ...
IDENTIFICATION OF NOVEL NATURALLY OCCURRING GENETIC INTERACTIONS USING INTER-PERSON VARIATION AND VIRUS DYNAMICS IN HEPATITIS C VIRUS AND HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS.
(Johns Hopkins University, 2015-08-14)
Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are two chronic viral infections of humans for which no vaccine exists. considerable research effort has focused on in vitro, ex vivo, and animal models due ...
Exploring the social context of sex and HIV/STI risk of recently released black men in Baltimore City.
(Johns Hopkins University, 2016-01-20)
Background: Black males comprise the largest group of US adults currently incarcerated, accounting for more than 30% of all males behind bars with rates nearly 6 times greater than those of white males. With evidence ...
The Epidemiology of Age-Associated Conditions Among Individuals Living with HIV in North America
(Johns Hopkins University, 2016-10-28)
Background:
Individuals receiving antiretroviral therapy (ART) for their HIV infection are getting older, but optimal management of care is complicated by the development of age-associated comorbidities. The goals of this ...
Cancer outcomes among people with HIV in North America in the era of antiretroviral therapy
(Johns Hopkins University, 2018-05-17)
Background: Poorer cancer outcomes have been observed for people with HIV (PWH) including more advanced stage at diagnosis, lower uptake of cancer treatment, and higher mortality. However, these results have not been ...
Anti-HIV Drug Human Biotransformation and Structure-Activity Relationship of Pregnane X Receptor Activation
(Johns Hopkins University, 2016-11-28)
With the advent of antiretroviral drug therapy in the late 1980s, human immunodeficiency virus (HIV) is no longer a death sentence, but remains to be a chronic disease. Of concern, however, an estimated 2.1 million individuals ...