Now showing items 1-10 of 17
Joint Spatial-Angular Sparse Coding, Compressed Sensing, and Dictionary Learning for Diffusion MRI
(Johns Hopkins University, 2018-03-02)
Neuroimaging provides a window into the inner workings of the human brain to diagnose and prevent neurological diseases and understand biological brain function, anatomy, and psychology. Diffusion Magnetic Resonance Imaging ...
Label Free CEST MRI Detection of Hydrogen Peroxide and its Applications in Monitoring Oxygen Delivery for Tissue Engineering
(Johns Hopkins University, 2017-05-02)
One of most formidable challenges in stem cell therapy is the initial hypoxia due to the lack of blood supply. Among the numerous oxygen-supplying systems that have been developed, hydrogen peroxide is suggested to be a ...
Image Guided Robots for Urology
(Johns Hopkins University, 2014-03-20)
This dissertation addresses the development of medical image-guided robots and their applications in urology. Image-guided robots integrate medical image information with robotic precision to assist the planning and execution ...
Advancing Magnetic Resonance Spectroscopy and Endoscopy with Prior Knowledge
(Johns Hopkins University, 2014-06-09)
Reconstruction is key to the generation of anatomic, functional and biochemical information in the field of Magnetic Resonance (MR) in medicine. Here, prior knowledge based on various conditions is utilized through ...
GREMLIN: Graph Estimation From MR Images Leading to Inference in Neuroscience
(Johns Hopkins University, 2016-05-02)
In recent years there has been a growing desire to understand the structure and function of the human brain. Approximately 1 in 5 adults suffers from mental illness, and many of these illnesses, including Alzheimer's ...
Statistical methods for epigenetic data and structural magnetic resonance imaging
(Johns Hopkins University, 2016-04-04)
This dissertation introduces novel statistical methods for the analysis of high-dimensional biomedical data. First, we present a normalization method for DNA methylation microarray data, called Functional normalization ...
NOVEL MRI APPROACHES FOR QUANTITATIVE ASSESSMENT OF CORONARY ARTERIES AND VENTRICULAR FUNCTION
(Johns Hopkins University, 2014-06-02)
Despite advances in screening techniques and prevention guidelines, cardiovascular disease remains the leading non-communicable disease with 17 million deaths worldwide in 2008. Approximately 6% of American adults had a ...
Steady-state Susceptibility Contrast MRI of Breast Cancer Angiogenesis: Preclinical Validation and Application
(Johns Hopkins University, 2014-02-07)
Angiogenesis is essential to the growth and spread of cancer, making it a promising therapeutic target. However, no anti-angiogenic drug is currently approved to treat breast cancer. Furthermore, there are no clinically ...
DEVELOPMENT AND APPLICATION OF NOVEL PHYSIOLOGICAL MRI METHODS TO IMAGE CHANGES IN OXYGENATION
(Johns Hopkins University, 2014-01-24)
This dissertation details the application of novel MRI methods (VASO and APT MRI) to acute stroke as well as the work to develop a novel MRI technique to image oxygenation in the brain.
STATISTICAL METHODS FOR AUTOMATIC BRAIN SEGMENTATION
(Johns Hopkins University, 2014-12-18)
Background: Automatic segmentation of the brain into cerebrospinal fluid (CSF), grey matter (GM), and white matter (WM) has been of interest for over twenty years. As magnetic resonance imaging (MRI) has improved and new ...