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The epidemiology of malaria and challenges to elimination in a low transmission setting in southern Zambia
(Johns Hopkins University, 2016-07-11)
Background: Recently, malaria has become a major global health priority. As a result there has been renewed interest in malaria control, elimination, and eradication. Zambia is one of the Elimination 8 countries and one ...
Optimization of Antimalarial Drug Regimens in a Cytocidal Murine Malaria Model
(Johns Hopkins University, 2018-04-25)
Statement of Problem: Although malaria is a preventable and curable disease, over 200 million cases and 400,000 deaths were reported in 2016, with the burden of disease borne predominantly by young African children. ...
Asymptomatic P. vivax Malaria Burden and Naturally-Acquired Humoral Response to PvMSP1-19 in a Low Endemic Malaria Area in the Peruvian Amazon Basin
(Johns Hopkins University, 2016-01-13)
Objective: P. vivax (Pv) malaria is the most widely distributed human malaria species in the world, affecting millions of people annually, and the most prevalent species in the Americas. One of the main challenges for the ...
Understanding Mechanisms of Sustained Malaria Transmission in Zambia Through Plasmodium falciparum Genetics
(Johns Hopkins University, 2018-12-06)
Malaria remains an enormous public health burden, particularly in sub-Saharan Africa where it is among the leading causes of childhood mortality. Recently, renewed global commitment to malaria elimination has laid the ...
Risk Profiling of Malaria Epidemiology in Rural Bangladesh
(Johns Hopkins University, 2016-09-09)
Background. Of 214 million estimated new malaria cases worldwide in 2015, 10% were from south-east Asia. Bangladesh is one of the 95 countries with ongoing malaria transmission. Of 13 malaria endemic districts in Bangladesh, ...
The impact of targeted IRS, vector dynamics, and population movement on malaria in a high-transmission setting in northern Zambia
(Johns Hopkins University, 2018-04-13)
Background: The scale-up of malaria control efforts has led to a global decline in malaria burden, but progress has stalled or reversed in high-transmission regions. In Zambia, malaria cases increased annually since 2009 ...
EPIDEMIOLOGY OF RESURGENT MALARIA IN EASTERN ZIMBABWE: RISK FACTORS, SPATIO-TEMPORAL PATTERNS AND PROSPECTS FOR REGAINING MALARIA CONTROL
(Johns Hopkins University, 2015-11-04)
Despite recent reductions in malaria morbidity and mortality due to the scale up of malaria interventions, malaria remains a public health problem in sub-Saharan Africa. A recent resurgence in malaria, in areas where malaria ...
Nothing but Nets: The History of Insecticide-Treated Nets in Africa, 1980s-Present
(Johns Hopkins University, 2017-10-06)
Insecticide-treated bed nets (ITNs) have become a main pillar of global malaria control in the twenty-first century, distributed by the millions annually across Africa and the global South. Understood as ‘evidence-based,’ ...
Challenges and opportunities for pursuing malaria elimination in Peru
(Johns Hopkins University, 2018-10-24)
Recent history suggests that malaria can be eliminated in low-endemic countries, and there is a growing interest among key stakeholders from Peru to plan accordingly and achieve malaria elimination with a comprehensive ...
INVESTIGATING THE BIOLOGY AND BEHAVIOR OF ANOPHELES SQUAMOSUS AND ITS ROLE IN RESIDUAL MALARIA TRANSMISSION IN SOUTHERN ZAMBIA
(Johns Hopkins University, 2019-04-15)
In the last decade, malaria cases in Southern Zambia have declined by 90% due in part to national control efforts. Despite this dramatic reduction, prevalence has remained near 1-2% for the past several years. In 2011, ...