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The Effect of Buprenorphine on HIV RNA Load Distribution and Viral Suppression
(Johns Hopkins University, 2020-04-28)
Opioid use is prevalent among people with HIV (PWH) and can delay time to viral suppression. Use of buprenorphine (BUP), an opioid agonist therapy, may improve HIV outcomes in HIV care settings. We estimated the marginal ...
Visualizing HOPE: Encouraging HIV-Positive Organ Transplantation Using Novel Modular Animations
(Johns Hopkins University, 2020-03-24)
HIV+ candidates in need of organ transplantation face an increased risk of mortality while on the organ waitlist and decreased access to transplantation compared to HIV-uninfected (HIV-) candidates. Fortunately, HIV+ donor ...
Violence victimization and virologic failure among adolescents and young adults living with HIV in Zambia
(Johns Hopkins University, 2020-01-07)
Background: Data are lacking on the prevalence and perpetrators of violence against adolescents and young adults (AYA) living with HIV in sub-Saharan Africa and how violence may relate to HIV outcomes. This dissertation ...
Stigma, Citizenship, and the Transition to Community-based HIV Care Among People Returning from Incarceration
(Johns Hopkins University, 2020-03-27)
Background
People in prisons and jails are a key population for HIV prevention and control. Despite high rates of HIV treatment initiation and retention inside places of detention, people returning from incarceration fail ...
Assessing the impact of targeted screening and treatment of diabetes and hypertension among adults living with HIV in Nairobi, Kenya
(Johns Hopkins University, 2020-04-20)
Introduction
Expanded access to ART and subsequent improvements in life expectancy have led to an HIV population that is increasingly at risk for many age-associated comorbidities. The future health of people living with ...
ANALYZING THE MICRO-SCALE SPATIAL DYNAMICS OF HIV TRANSMISSION IN LAKE VICTORIA FISHING COMMUNITIES
(Johns Hopkins University, 2020-04-29)
Introduction. Fishing communities in the Lake Victoria basin have among the highest HIV incidence rates and disease burden globally. Understanding the local drivers of transmission can inform ongoing epidemic control ...
THE LATENT RESERVOIR IN ELITE CONTROLLERS AND FACTORS THAT AFFECT THE SUPPRESSIVE CAPACITIES OF IMMUNE EFFECTOR CELLS IN HIV POSITIVE INDIVIDUALS
(Johns Hopkins University, 2020-06-17)
Our inability to efficiently target and eliminate the latent reservoir remains the biggest barrier to a cure to HIV/AIDS. Accordingly, there exist several ongoing efforts to not only understand the reservoir in varied ...
Exploring the context and role of quality of care on HIV outcomes among female sex workers in the Dominican Republic
(Johns Hopkins University, 2021-01-08)
Female sex workers (FSWs) experience a substantially disproportionate burden of HIV. In the Dominican Republic (DR), FSWs have nearly five times greater odds to be living with HIV compared to other adults. Despite interventions ...
ACTIVATION OF NLRP3 INFLAMMASOME BY HIV
(Johns Hopkins University, 2021-05-06)
Chronic inflammation is a significant contributor to many of the leading causes of death. One driver of chronic inflammation is chronic viral infection; specifically, people infected with Human Immunodeficiency Virus (HIV) ...
PHYLOGENETIC AND NETWORK APPROACHES TO UNDERSTANDING HIV AND HEPATITIS C TRANSMISSION DYNAMICS AMONG KEY POPULATIONS IN INDIA
(Johns Hopkins University, 2021-04-05)
Injection drug use is increasingly accounting for new HIV and hepatitis C virus (HCV) infections in low- and middle-income countries (LMICs); however, much of what is known about transmission among people who inject drugs ...