Now showing items 1-1 of 1
The Effect of Human Immunodeficiency Virus Type-1 Coreceptor Preference on Entry and Tropism Specific Phenotypes
(Johns Hopkins University, 2014-07-08)
During HIV type 1 (HIV-1) entry, trimers of viral gp120 proteins attach to CD4 molecules and to CCR5 or CXCR4 coreceptors on the target cell. A virus is defined as R5 tropic if it uses CCR5 coreceptors and X4 tropic if it ...