Now showing items 1-4 of 4
CENTRAL NERVOUS SYSTEM PENETRATION OF COMBINATION ANTIRETROVIRAL THERAPY: THE CEREBROSPINAL FLUID (CSF) RISK SCORE, THE BURDEN OF CSF VIRAL ESCAPE, AND DEPRESSION IN PERSONS WITH HIV
(Johns Hopkins University, 2013-11-07)
BACKGROUND: Detectable cerebrospinal (CSF) HIV ribonucleic acid (RNA) is associated with central nervous system (CNS) complications including neurocognitive impairment and depression. Major depressive disorder (MDD) is the ...
TRENDS, PREDICTORS AND OUTCOMES ASSOCIATED WITH UNSTRUCTURED TREATMENT INTERRUPTIONS AMONG HIV-POSITIVE INDIVIDUALS ON ANTIRETROVIRAL THERAPY IN CANADA
(Johns Hopkins University, 2013-10-23)
Background The expanded use of combination antiretroviral therapy (cART) has dramatically enhanced the quality of care and life expectancy of HIV-positive individuals. However, incomplete adherence and treatment interruptions ...
REPLICATION-COMPETENT NON-INDUCED PROVIRUSES IN THE LATENT RESERVOIR INCREASE BARRIER TO HIV-1 CURE
(Johns Hopkins University, 2013-09-05)
Antiretroviral therapy (ART) fails to cure HIV-1 infection because latent proviruses persist in resting CD4+ T cells. T cell activation reverses latency, but >99% of proviruses are not induced to release infectious virus ...
CIGARETTE SMOKING BEHAVIORS AMONG PEOPLE LIVING WITH HIV: ASSOCIATIONS WITH INDIVIDUAL- AND SOCIAL-LEVEL CHARACTERISTICS
(Johns Hopkins University, 2013-09-20)
INTRODUCTION: Smoking is endemic among people with HIV and associated with morbidity and mortality. Little research has been conducted among smokers with HIV. Research has focused on examining individual-level characteristics ...