Now showing items 1-10 of 733
Emerging Non-Hereditary Risk Factors for Stroke
(Johns Hopkins University, 2014-04-04)
Stroke is a leading cause of death and disability globally. The vast majority of all strokes occur in low- and middle-income countries, where data are least available to guide clinical decision-making and health policy. ...
Exploration of Novel Small Molecule Phenelzine Analogue LSD1 Inhibitors
(Johns Hopkins University, 2014-09-25)
Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme that oxidatively cleaves methyl groups from monomethyl and dimethyl Lys4 of histone H3 (H3K4me1, H3K4me2) and can contribute to gene silencing. We designed and ...
SUPERCRITICAL CARBON DIOXIDE (scCO2) PROCESSING OF DISPERSED POLYMER/CLAY NANOCOMPOSITES: STRUCTURAL AND BARRIER PROPERTIES
(Johns Hopkins University, 2014-05-29)
Improved polymeric packaging materials have significantly economic and environmental impact on food, beverage and other industries. In this dissertation, we developed polymer/clay nanocomposites, by incorporating impermeable ...
STEM CELL AND HYPOXIA-BASED APPROACHES TO ENGINEERING BLOOD VESSELS
(Johns Hopkins University, 2014-05-19)
The success of tissue regenerative therapies is contingent upon functional and multicellular vasculature within the redeveloping tissue. Endothelial cells (ECs), which comprise the vasculature’s inner lining, are intrinsically ...
ANALYSIS OF THE BANKRUPTCY PROVISION FOR STUDENT LOAN DEBT
(Johns Hopkins University, 2014-05-12)
Paul Weinstein email@example.com
DENGUE INFECTION IN PUERTO MALDONADO, PERU: HUMAN MIGRATION AND ECONOMIC IMPACT
(Johns Hopkins University, 2014-10-10)
Dengue virus (DENV) is an arbovirus with global distribution that affects more than 100 countries worldwide. This Flavivirus was reintroduced to Peru in the 1990s and has disseminated across several areas in the country, ...
Cognitive processes of letter and digit identification
(Johns Hopkins University, 2015-01-20)
Letter identification, the process of determining letter identities and their positions from a visual stimulus, has a long research history. Debate remains concerning the levels of representation involved, as well as the ...
Developing Membrane Active Peptides for Endosomal Escape of Macromolecules
(Johns Hopkins University, 2015-03-16)
Membrane Active Peptides (MAPs) are an important class of short protein sequences that hold the potential to be used for a number of varied purposes such as antibacterial, antiviral, and drug delivery based therapies. ...
MULTISCALE MODELING OF REACTIVE Ni/Al NANOLAMINATES
(Johns Hopkins University, 2013-10-20)
This dissertation employs multiscale modeling for the purpose of investigating reactions occurring in reactive Ni/Al nanolaminates. These are comprised of alternating layers of Ni and Al that can react exothermically upon ...
IN VIVO DIFFUSION WEIGHTED MAGNETIC RESONANCE SPECTROSCOPY IN MULTIPLE SCLEROSIS
(Johns Hopkins University, 2015-03-26)
Multiple sclerosis (MS) is a complex CNS disease in which inflammation, demyelination and neuroaxonal degeneration are concurrent processes. MS therapies developed to date are directed at the immune-mediated, inflammatory ...