Now showing items 11-16 of 16
HIV-1 Viral Infectivity Factor Recruitment of Cellular Protein Complexes to Counter Host Antiviral Response
(Johns Hopkins University, 2014-02-26)
Human cytidine deaminase apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) proteins (e.g. APOBEC3G) provide a potent host defense against HIV, in the absence of viral infectivity factor (Vif). ...
THE CHANGING HIV EPIDEMIC IN THE MODERN ANTI-RETROVIRAL THERAPY ERA
(Johns Hopkins University, 2014-03-14)
During the early 21st century HIV underwent a transition from an invariably terminal illness to a manageable chronic condition. Much of this change is due to improvements in medication and management. Concurrently, treatment ...
Mobile Health (mHealth) Assessment of Illicit Drug Use Among Community Dwelling Drug Users in Baltimore, MD
(Johns Hopkins University, 2014-07-28)
Background: Substance abuse is a chronic disease often characterized by multiple attempts at abstinence, frequent relapse and is associated with a range of morbidities and mortality. This dissertation utilizes a mobile ...
Plasma hepcidin concentrations and factors associated with hemoglobin levels in infants and young children in Zimbabwe
(Johns Hopkins University, 2014-03-07)
Iron metabolism is very dynamic over the first year of life. Anemia is common in sub-Saharan African infants, particularly in the context of HIV infection. Hepcidin, a peptide hormone whose synthesis is simultaneously ...
A TEST OF AN INTERVENTION TO PROMOTE PAP TESTING IN A GROUP OF WOMEN LIVING WITH HIV
(Johns Hopkins University, 2014-07-02)
Background: Cervical cancer is the second most common type of cancer among women worldwide. Women with human immunodeficiency virus (HIV) bear a disproportionate burden of cervical cancer and its precursor, cervical ...
Oral HPV Infection and Head and Neck Squamous Cell Carcinoma in HIV-infected and HIV-uninfected Individuals
(Johns Hopkins University, 2014-01-26)
Background: Oral HPV infection is etiologically associated with a subset of Head and Neck Squamous Cell Carcinomas (HNSCCs). However, the natural history and risk factors of this infection are largely unexplored particularly ...