Now showing items 11-14 of 14
Investigating the Motility of Plasmodium
(Johns Hopkins University, 2017-04-20)
Malaria is a life-threatening disease and the search for vaccine targets to the malaria parasite Plasmodium continues to be of utmost importance. Antibody mediated vaccines to the pre-erythrocytic stage of Plasmodium ...
Measuring Child Health Coverage: Validation of Maternal-Reported Care-seeking and New Methods for Estimating Coverage of Appropriate Management of Childhood Illness
(Johns Hopkins University, 2017-03-27)
Problem Statement: Accurate data on coverage of health interventions is required for continued reduction in child mortality. This study assessed the validity of the standard indicator on care-seeking for child illness and ...
IMPROVING THE EFFICIENCY OF REACTIVE SCREEN-AND-TREAT FOR MALARIA ELIMINATION IN SOUTHERN ZAMBIA
(Johns Hopkins University, 2018-04-18)
Background: Malaria screen-and-treat (called Step-D in Zambia) is a reactive case detection strategy in which passively detected malaria cases trigger community health workers (CHWs) to screen for secondary cases within a ...
PHARMACODYNAMIC ANALYSIS OF P. FALCIPARUM KILL RATES IN MONOTHERAPY CLINICAL TRIALS AND INVESTIGATION OF QUORUM SENSING-DEPENDENCE OF EARLY KILL RATES IN MURINE MODELS
(Johns Hopkins University, 2018-04-26)
In treating malaria infections, rapid pharmacodynamic kill rates avert death and hinder drug resistance. We explored the recent 4 decades of published P. falciparum monotherapy drug trials featuring over 17,000 patients ...