Now showing items 1-5 of 5
The Ubiquity of Iodotyrosine Deiodinase: Identification of its Signature Sequence and Functional Analysis in a Model Invertebrate
(Johns Hopkins University, 2016-08-16)
Iodotyrosine deiodinase (IYD) serves a critical role in iodide conservation through salvage of iodide from mono- and diiodotyrosine (I-Tyr and I2-Tyr), the by-products of thyroid hormone (TH) synthesis. Genomic data suggested ...
Physiological control of Drosophila ovarian stem cell lineages
(Johns Hopkins University, 2016-07-05)
In order to support tissue function, adult stem cell activity must respond to organismal dietary status and whole-body physiology. The complex signaling networks impinging on stem cells, however, are not fully understood. ...
OLFACTORY PROCESSING IN OVIPOSITION BEHAVIOR OF DROSOPHILA MELANOGASTER
(Johns Hopkins University, 2016-10-10)
How does the brain make sense of complex mixtures of smells? An animal’s olfactory system is capable of detecting and distinguishing hundreds (perhaps thousands) of chemicals, and translating those inputs into useful ...
THE ROLE OF ADP RIBOSYLATION FACTOR GTPASES IN MYOBLAST FUSION IN DROSOPHILA
(Johns Hopkins University, 2016-04-04)
Myoblast fusion is a crucial step in myogenesis and muscle regeneration and is highly conserved across many species. A guanine nucleotide exchange factor for the Arf GTPase, Loner, is required for myoblast fusion in ...
ONCOGENIC MYC DISRUPTS THE MOLECULAR CLOCK AND METABOLISM IN CANCER CELLS AND DROSOPHILA
(Johns Hopkins University, 2016-03-25)
Circadian rhythm is a biological rhythm with a period about 24 hours, which coordinates the organismal biological processes with environmental day and night cycle. This 24-hour rhythm is exhibited in every cell in the ...