Now showing items 1-4 of 4
CIGARETTE SMOKING BEHAVIORS AMONG PEOPLE LIVING WITH HIV: ASSOCIATIONS WITH INDIVIDUAL- AND SOCIAL-LEVEL CHARACTERISTICS
(Johns Hopkins University, 2013-09-20)
INTRODUCTION: Smoking is endemic among people with HIV and associated with morbidity and mortality. Little research has been conducted among smokers with HIV. Research has focused on examining individual-level characteristics ...
CENTRAL NERVOUS SYSTEM PENETRATION OF COMBINATION ANTIRETROVIRAL THERAPY: THE CEREBROSPINAL FLUID (CSF) RISK SCORE, THE BURDEN OF CSF VIRAL ESCAPE, AND DEPRESSION IN PERSONS WITH HIV
(Johns Hopkins University, 2013-11-07)
BACKGROUND: Detectable cerebrospinal (CSF) HIV ribonucleic acid (RNA) is associated with central nervous system (CNS) complications including neurocognitive impairment and depression. Major depressive disorder (MDD) is the ...
REPLICATION-COMPETENT NON-INDUCED PROVIRUSES IN THE LATENT RESERVOIR INCREASE BARRIER TO HIV-1 CURE
(Johns Hopkins University, 2013-09-05)
Antiretroviral therapy (ART) fails to cure HIV-1 infection because latent proviruses persist in resting CD4+ T cells. T cell activation reverses latency, but >99% of proviruses are not induced to release infectious virus ...
TRENDS, PREDICTORS AND OUTCOMES ASSOCIATED WITH UNSTRUCTURED TREATMENT INTERRUPTIONS AMONG HIV-POSITIVE INDIVIDUALS ON ANTIRETROVIRAL THERAPY IN CANADA
(Johns Hopkins University, 2013-10-23)
Background The expanded use of combination antiretroviral therapy (cART) has dramatically enhanced the quality of care and life expectancy of HIV-positive individuals. However, incomplete adherence and treatment interruptions ...