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CALCIUM AT THE PUMP: REGULATION OF INTRACELLULAR CALCIUM BY SECRETORY PATHWAY CALCIUM ATPASE ISOFORM 2 (SPCA2) IN MODELS OF LACTATION AND BREAST CANCER
(Johns Hopkins University, 2013-09-06)
Secretory Pathways Calcium ATPase 2 (SPCA2) is a non-redundant isoform of SPCA expressed in highly secretory cells. In this study we aimed to investigate physiological regulation of SPCA2 as a possible regulator of calcium ...
THE HOMEOBOX PROTEIN HOXC10 IS OVEREXPRESSED IN BREAST CANCER AND INCREASES RESISTANCE TO CHEMOTHERAPY
(Johns Hopkins University, 2013-10-16)
Background. Drug resistance is a major limiting factor in the success of targeted cancer therapies resulting in failure of treatment. A molecular understanding of the underlying mechanisms is essential to predict, prevent ...