Now showing items 1-3 of 3
ONCOGENIC PROPERTIES AND TARGETING OF NTRK1 IN BREAST CANCER
(Johns Hopkins University, 2018-03-23)
Triple negative breast cancers (TNBC) comprise a highly aggressive cancer subtype with high mortality rates, high frequency of metastatic disease and a lack of targeted therapies. A fraction of these cancers also demonstrate ...
CCL9 INDUCED BY TGF-β SIGNALING IN MYELOID CELLS ENHANCES TUMOR CELL SURVIVAL IN THE PREMETASTATIC LUNG
(Johns Hopkins University, 2015-04-09)
The majority of cancer patients die from metastasis. To achieve metastasis, tumor cells must first survive and then proliferate to form colonies. Compelling data have shown the indispensable participation of host ...
The Role of Hypoxia-Regulated RhoB Expression in Breast Cancer Tumorigenesis and Metastasis
(Johns Hopkins University, 2017-05-05)
Although Rho GTPases RhoA, RhoB, and RhoC share more than 85% amino acid sequence identity, they may play very distinct roles in tumor progression. RhoA and RhoC have been suggested in many studies to contribute positively ...