Now showing items 516-535 of 1303

    • Gamers, Hunters, Provocateurs: Digital Mediations of Violence, Gender and Faith in the Arab World 

      Grove, Nicole Sunday (Johns Hopkins UniversityUSA, 2015-01-26)
      My dissertation examines how digital media and communications technologies shape responses to gendered violence, human security, and women’s rights in the Middle East. I combine discourse analysis with a material investigation ...
    • The Gaussian Isoperimetric Problem and the Self-Shrinkers of Mean Curvature Flow 

      McGonagle, Matthew William (2014-07-06)
      We record work done by the author joint with John Ross [27] on stable smooth solutions to the gaussian isoperimetric problem, and we also record work done by the author [26] on two-dimensional self-shrinkers of any ...
    • Gender Differences in Depressive Symptoms in Kumasi, Ghana 

      Psaki, Stephanie (Johns Hopkins UniversityUSA, 2013-09-02)
      Background: Depression is an important public health issue globally, and accounts for an increasingly large proportion of disease burden in low-income countries. Depression is twice as common in women as men. Despite the ...
    • Gene Discovery and Glutamate Signaling Defects in Intellectual Disability and Autism 

      Niranjan, Tejasvi S (2015-03-24)
      Neurodevelopmental disorders are a common class of brain disorders that affect up to 1 in 6 children in the industrialized world. They include a range of diseases, including Attention Deficit Hyperactivity Disorder, Autism ...
    • GENE EXPRESSION ANALYSIS IN MEASLES VIRUS RESEARCH 

      Zilliox, Michael (2007-03-26)
      The sequencing of the human genome ushered in the era of high-throughput biology. Rapid, whole cell analysis is replacing the molecular reductionist approach of the last century. Microarrays are one of the main high-throughput ...
    • GENE EXPRESSION PROFILING IN ISCHEMIC AND NONISCHEMIC CARDIOMYOPATHY 

      Kittleson, Michelle Maya (2006-08-03)
      Background Despite our growing understanding of the pathophysiology and management of heart failure, there exist no strategies to individualize therapy using predictors of long-term prognosis and response to therapy. ...
    • Generalizations, extensions and applications for principal component analysis 

      Yue, Chen (Johns Hopkins UniversityUSA, 2016-02-24)
      Principal component analysis (PCA) is one of the most important dimension reduction technique. It is widely used in many applications including economics, finance and medical research. In this research, several novel ...
    • Genetic Disruption of Ki-67 Results in Decreased Clonogenic Proliferation 

      Cidado, Justin (2014-03-19)
      Two well-known hallmarks of cancer are the abilities to sustain proliferation and invade surrounding tissue, and pathways involved in these processes have been scrutinized for possible therapeutic targets in recent years. ...
    • Genetics and mechanisms of telomere-mediated lung disease 

      Stanley, Susan (Johns Hopkins UniversityUSA, 2017-01-04)
      Chronic lung disease is the third leading cause of death in the United States. Emphysema and pulmonary fibrosis are two of the most common forms and are thought in part to represent a premature aging phenotype in the lung. ...
    • Genocide: A Political Genealogy 

      Meiches, Benjamin A (Johns Hopkins UniversityUSA, 2015-07-01)
      The Polish jurist Raphael Lemkin added the concept of genocide to our vocabulary barely seventy years ago. In the ensuing decades, ‘genocide’ has become a highly politicized term employed in discussions of ethics, law, and ...
    • GENOME-WIDE STUDIES ON POST-TRANSCRIPTIONAL REGULATION 

      McGeachy, Anna (Johns Hopkins UniversityUSA, 2016-06-08)
      Regulation of gene expression is essential for cellular survival and complex responses or phenotypes. Improvements in sequencing technology enable investigation of RNA transcription as a means to understand complex biological ...
    • Genomic Data-Based Models of Growth Factor Signaling for Personalized Cancer Therapy Selection 

      Bender, Robert Joseph (2014-11-07)
      The genetic heterogeneity of cancer creates patient-to-patient variability that makes it difficult to predict whether the patient will respond to a treatment. This is particularly true for VEGF-targeting therapies, for ...
    • Genomics and Epigenomics of Common Human Metabolic and Heart Disease 

      Multhaup, Michael Lewis (Johns Hopkins UniversityUSA, 2015-02-11)
      The field of epigenetics is rapidly becoming recognized as playing an essential part in explaining common human disease. Here we probe DNA methylation in diabetes mellitus and associated metabolic phenotypes and coronary ...
    • The Genomics of Oral Poliovirus Vaccine Response in Bangladeshi Infants 

      Wojcik, Genevieve Lianne (2013-11-05)
      The success of Oral Poliovirus Vaccine (OPV) in eradicating poliovirus has set an example for the immense potential of oral vaccines in preventing enteric infections. It is widely considered the standard for oral vaccines ...
    • GEOCHEMICAL SIGNATURES OF WEATHERING AND SURFACE WATER CHEMISTRY IN THE LATE ARCHEAN 

      Hao, Jihua; 0000-0003-3657-050X (Johns Hopkins UniversityUSA, 2016-11-30)
      Earth’s Archean surface environment was important for the origin and evolution of life. Here, it is proposed that the pH2,g controlled the redox state of the Archean atmosphere, consistent with the stabilities of detrital ...
    • GEOMETRIC APPROACHES TO DISCRIMINATIVE TRAINING 

      Cao, Yuan (Johns Hopkins UniversityUSA, 2016-02-04)
      Discriminative training as a general machine learning approach has wide applications in tasks like Natural Language Processing (NLP) and Automatic Speech Recognition (ASR). In this thesis, we are interested in online methods ...
    • Geometric Motion Planning Methods for Robotics and Biological Crystallography 

      Yan, Yan (2014-02-18)
      This dissertation presents several novel approaches to motion planning problems by incorporating useful geometrical models. Two different approaches are addressed in the contexts of biological crystallography and robot ...
    • Geospatial Health Equity in the US and India 

      Brady, Eoghan Séamus; 0000-0003-0075-5406 (Johns Hopkins UniversityUSA, 2017-04-19)
      Background Health equity is a public health priority in the US and globally, as people and their governments view large, objectively measurable health disparities through a lens of social justice. Inequities in child and ...
    • GIOVANNI ANTONIO DA PORDENONE: ARTISTIC AMBITION AND THE CHALLENGE OF THE LOCAL 

      Di Resta, Jason (Johns Hopkins UniversityUSA, 2015-05-25)
      This dissertation challenges how we understand the relationship between style and location in the case of the traveling painter Giovanni Antonio da Pordenone (ca. 1484–1539). In moving throughout Italy at the start of the ...
    • GLOBAL ANALYSIS OF SUMO E3 LIGASE SPECIFICITY UNCOVERS CROSSTALK-MEDIATED KINASE ACTIVATION 

      Uzoma, Ijeoma K (2014-03-25)
      Over 100 kinases were recovered as SUMO substrates in our assays which points to a global phenomenon of kinase regulation by SUMO modification. The studies presented in chapter 4 describe our efforts to validate and ...