Browsing ETD -- Doctoral Dissertations by Title
Now showing items 3006-3025 of 4630
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PAIRS OF BOOSTED HIGGS AND WHERE TO FIND THEM
(Johns Hopkins UniversityUSA, 2021-09-08)A search is presented for pair production of the standard model Higgs boson using data from proton-proton collisions at a centre-of-mass energy of 13 TeV, collected by the CMS experiment at the CERN LHC in 2016–2018, and ... -
PALLIATIVE MEDICINE COMPETENCY EDUCATION IN EMERGENCY MEDICINE RESIDENCY TRAINING: A SURVEY OF EMERGENCY MEDICINE EDUCATION LEADERS
(Johns Hopkins University, 2014-05-30)Background: Emergency physicians care for patients with palliative and hospice needs. More than 75 percent of patients visit the ED in the last 6 months of life, and two-thirds of those patients die while hospitalized. ... -
Pan-genomics and the structural diversity of plant genomes
(Johns Hopkins UniversityUSA, 2021-10-22)A central task of genetics research is to uncover genotypes linked to important phenotypes. However, many genomic loci are incompletely or inaccurately represented in genetics studies, thus obscuring their function and ... -
Pancreatic Cancer Immunotherapy: T-Cell Receptor Sequencing and Personalized Gene Fusion Vaccines
(Johns Hopkins UniversityUSA, 2017-08-24)Immunotherapy has struggled to reduce the high mortality rate of pancreatic cancer,in part due to the low mutation burden and immunosuppressive microenvironment associated with the disease. Early successes have been limited ... -
Pancreatic Progenitor Cells in Mice
(Johns Hopkins UniversityUSA, 2014-07-25)We generated a novel transgenic mouse expressing a tdTomato fluorophore, as well as a Strep/Flag-tagged version of Ptf1a from the native Ptf1a locus. I crossed this mouse line with the well-characterized Pdx1-GFP mouse, ... -
PARAMETRICALLY HOMOGENIZED CONSTITUTIVE MODELS FOR TITANIUM ALLOYS
(Johns Hopkins UniversityUSA, 2020-12-21)Structural analysis of heterogeneous materials using phenomenological constitutive models, is often faced with inaccuracies stemming from the lack of connection with the material microstructure and underlying physics. Pure ... -
PARAMETRICALLY HOMOGENIZED CONTINUUM DAMAGE MECHANICS (PHCDM) MODELS FOR UNIDIRECTIONAL FIBER-REINFORCED COMPOSITES
(Johns Hopkins UniversityUSA, 2021-07-14)Fiber reinforced composites are widely used in aerospace, energy, protective armors and other applications that require materials with high strength-to-weight ratios, impact resistance, durability, etc. Damage in such ... -
Parametrically Homogenized Crystal Plasticity Model for Nickel-based Superalloys: Intragranular Microstructures To Polycrystalline Aggregates
(Johns Hopkins UniversityUSA, 2020-08-31)The deformation mechanics of nickel-based superalloys at every length scale are influenced by a unique array of dislocation mechanisms evolving at the nanoscale. The origin of the lower scale phenomena within a single ... -
Parent and Family Resonses to a Child Undergoing BMT During Transitions in Care
(Johns Hopkins UniversityUSA, 2016-11-04)Background Pediatric blood and marrow transplantation (BMT) is an intense treatment reserved for life-threatening oncologic, hematologic, and immunologic illnesses of childhood. While BMT offers hope for cure, the intensity ... -
PARENT INTERVENTION TO STRENGTHEN MILITARY CHILD SCHOOL READINESS AT MARINE CORPS AIR STATION YUMA, ARIZONA: A MIXED METHODS EVALUATION
(Johns Hopkins UniversityUSA, 2020-04-28)The development of school readiness competencies, vital for school success, may be jeopardized, especially for children of enlisted service members due to the unique challenges their military families face. After examining ... -
Parental Exposure to Occupational Asthmagens and Risk of Autism Spectrum Disorder
(Johns Hopkins UniversityUSA, 2015-04-10)Background: Autism spectrum disorder (ASD) is a diverse neurodevelopment disorder manifested by repetitive or stereotypic behaviors, and interaction and communication impairments. The etiology is not well understood, but ... -
Paris Mediates Mitochondrial Deficits and Dopaminergic Neuronal Loss In PINK1 and Parkin Linked Parkinson's Disease
(Johns Hopkins UniversityUSA, 2018-01-16)Parkinson’s disease (PD) is a common neurodegenerative movement disorder affecting more than five million people worldwide. Afflicted individuals present with an array of debilitating movement symptoms arising from the ... -
Part I: Super-resolution Microscopy Method Development Part II: Investigations of Transcription Regulation by Chromosomal Organization in Bacteria
(Johns Hopkins UniversityUSA, 2020-01-23)Part I: SMLM provides not only high-resolution images of molecular assemblies beyond the diffraction limit but also enables quantitative analysis of the dynamics and compositions. However, challenges in imaging and analysis ... -
Partial identification and testable implications in graphical models of observational data
(Johns Hopkins UniversityUSA, 2022-01-06)The classical approach to discovering scientific facts is through experimentation, in which the scientist can control relevant features of the environment and observe the outcome of interest. In some fields, such as ... -
Participation and Conflicting Objectives in The Era of Integrated Water Resources Management: A Case Study of São Paulo, Brazil
(Johns Hopkins UniversityUSA, 2017-02-27)The metropolitan region of São Paulo, Brazil experienced an unprecedented drought between 2013-2015, putting millions of people at risk of water shortages. The impending water crisis brought into question both the reliability ... -
Particle-obstacle interactions at low Reynolds number: implications for microfluidic applications
(Johns Hopkins University, 2013-10-20)In this thesis, we analyse the motion and interactions of a suspended (spherical) particle moving past a fixed (spherical or cylindrical) obstacle, as a means to better understand the underlying mechanisms of microfluidic ... -
PARTIES’ GROUP APPEALS AND THEIR IMPLICATIONS FOR INTER- AND INTRA-PARTY BEHAVIOR
(Johns Hopkins UniversityUSA, 2021-05-28)Parties’ group appeals, their structure, content, and influence on other aspects of party behavior are of great concern to those who study politics and political representation. As social groups are essential to the political ... -
Path Planning and Performance Evaluation Strategies for Marine Robotic Systems
(Johns Hopkins UniversityUSA, 2022-01-13)The field of marine robotics offers many new capabilities for completing dangerous missions such as deep-sea exploration and underwater demining. The harshness of marine environments, however, means that without effective ... -
Pathogenesis of Myocarditis and Inflammatory Dilated Cardiomyopathy: the Sign of Four
(Johns Hopkins UniversityUSA, 2014-04-10)Myocarditis and inflammatory dilated cardiomyopathy (DCMi) are major causes of heart failure in individuals below the age of 40. In the work presented in this dissertation, using a model of mouse experimental autoimmune ... -
PATHOGENIC MECHANISMS OF CITROBACTER RODENTIUM INFECTION IN IMMUNOCOMPROMISED ANIMALS
(Johns Hopkins UniversityUSA, 2020-10-22)Human attaching and effacing (A/E) pathogens enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC) are the leading causative agents for foodborne diseases, which lead to severe economic burden, ...