Now showing items 1-4 of 4

    • Direction Sensing During Collective Cell Migration 

      Cai, Danfeng (Johns Hopkins UniversityUSA, 2014-10-06)
      Collective cell migration is an important process not only in development but also in diseases. The Drosophila ovary, with its relatively simply structure, genetic tractability, and the compatibility with live imaging, is ...
    • GPR124 IS A NOVEL CO-ACTIVATOR OF CANONICAL WNT SIGNALING 

      Zhou, Yulian (Johns Hopkins UniversityUSA, 2015-05-26)
      Canonical Wnt signaling in endothelial cells (ECs) is required for vascularization of the central nervous system (CNS) and for formation and maintenance of barrier properties unique to CNS vasculature. Gpr124 is an orphan ...
    • MECHANISITIC STUDIES OF CHEMICAL BIOLOGY PROBES REGULATING MTOR PATHWAY 

      Li, Ruojing; 0000-0001-7559-3929 (Johns Hopkins UniversityUSA, 2016-12-29)
      Mechanistic target of rapamycin (mTOR) plays an essential role in sensing a myriad of environmental cues including nutrients and growth factor stimulation to regulate cell growth and proliferation. mTOR independently ...
    • Mechanisms of Yki-mediated transcriptional regulation of the Hippo signaling pathway 

      Qing, Yun (Johns Hopkins UniversityUSA, 2016-08-25)
      The Hippo signaling pathway is a conserved pathway in regulating organ size. Deregulation of the pathway also exerts crucial effects on cancer development. In Drosophila, the Hippo pathway restricts tissue growth by ...