Browsing ETD--Doctoral Dissertations by Subject "T cell receptor signaling"
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Understanding cytotoxic T lymphocyte function using models of primary immunodeficiencies
(Johns Hopkins UniversityUSA, 2016-07-11)CD8+ cytotoxic T lymphocytes (CTLs) are critical for the elimination of virally-infected cells, and defects in CTL responses can lead to primary immunodeficiencies and secondary lymphoproliferative syndromes. One such ...