Now showing items 1-2 of 2

    • Engineering Biomaterial Properties for T Cell Immunotherapy 

      Hickey, John Wirthlin; 0000-0001-9961-7673 (Johns Hopkins UniversityUSA, 2019-02-28)
      Immune cell therapies have revolutionized our idea of a drug. Essentially they are a living drug becoming increasingly used because of their specificity (antigen targeting), durability (memory cells), and success seen in ...
    • Identification of T cell derived KLK1b22 as a novel regulator of systemic metabolism 

      Arwood, Matthew Lee; 0000-0003-4737-9786 (Johns Hopkins UniversityUSA, 2018-03-28)
      In an effort to understand the role of mTORC1 in regulating T cell differentiation, we generated mice in which Rheb is selectively deleted in T cells (T-Rheb -/- mice). During the course of these studies we noted that the ...