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Engineering High-Affinity Supramolecular Polymers for Antibody Capture and Purification
(Johns Hopkins University, 2020-07-16)
Monoclonal antibodies (mAbs) have received considerable attention over the past three decades for the treatment of many diseases. With the significant titer improvement in cell culture processes, the mAb capture step using ...
ENGINEERING DNA-BASED NANOCHANNELS AND VESICLES FOR CONTROLLED MOLECULAR TRANSPORT
(Johns Hopkins University, 2021-05-03)
For the past two decades, synthetic transmembrane nanopores and nanochannels have become powerful tools in biosensing and single-molecule studies. Due to the ease of rational design and advancements in DNA functionalization, ...